MANABE Hiroyuki
Organization for Research Initiatives and Development
Associate Professor
Last Updated :2021/10/23

Researcher Profile and Settings

Profile and Settings

  • Research funding number

    80511386

Research Interests

  • flavor

Research Areas

  • Life sciences/Neuroscience - general

Academic & Professional Experience

  • Doshisha University, 2015/04 - Today
  • The University of Tokyo, 2011/04 - 2015/03

Academic Degrees

  • 博士(医学), 東京大学

Published Papers

  • Sharp wave-associated activity patterns of cortical neurons in the mouse piriform cortex.
    Katori K, Manabe H, Nakashima A, Eer D, Sasaki T, Ikegaya Y, Takeuchi H
    The European journal of neuroscience, 48(10)3246 - 3254, Aug. 2018, English, Research paper (scientific journal)
  • Multiple Approaches to the Investigation of Cell Assembly in Memory Research-Present and Future.
    Sakurai Y, Osako Y, Tanisumi Y, Ishihara E, Hirokawa J, Manabe H
    Frontiers in systems neuroscience, 1221 , 2018
  • Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat
    Yuma Osako, Tomoya Ohnuki, Yuta Tanisumi, Kazuki Shiotani, Hiroyuki Manabe, Yoshio Sakurai, Junya Hirokawa
    Current Biology, Elsevier BV, Apr. 2021, Research paper (scientific journal)
  • Bi-directional encoding of context-based odors and behavioral states by the nucleus of the lateral olfactory tract
    Yuta Tanisumi, Kazuki Shiotani, Junya Hirokawa, Yoshio Sakurai, Hiroyuki Manabe
    iScience, Elsevier BV, 24(4)102381 - 102381, Apr. 2021, Research paper (scientific journal)
  • Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs
    Tomoya Ohnuki, Yuma Osako, Hiroyuki Manabe, Yoshio Sakurai, Junya Hirokawa
    Communications Biology, Springer Science and Business Media LLC, 3(1), Dec. 2020, Research paper (scientific journal)
  • Encoding of odor information and reward anticipation in anterior cortical amygdaloid nucleus
    Kazuki Shiotani, Yuta Tanisumi, Junya Hirokawa, Yoshio Sakurai, Hiroyuki Manabe
    Cold Spring Harbor Laboratory, 20 Nov. 2020
  • Tuning of olfactory cortex ventral tenia tecta neurons to distinct task elements of goal-directed behavior
    Kazuki Shiotani, Yuta Tanisumi, Koshi Murata, Junya Hirokawa, Yoshio Sakurai, Hiroyuki Manabe
    eLife, eLife Sciences Publications, Ltd, 9, 04 Aug. 2020, Research paper (scientific journal)
  • Dynamics of memory engrams
    Shogo Takamiya, Shoko Yuki, Junya Hirokawa, Hiroyuki Manabe, Yoshio Sakurai
    Neuroscience Research, Elsevier BV, 15322 - 26, Apr. 2020, Research paper (scientific journal)
  • GABAergic neurons in the olfactory cortex projecting to the lateral hypothalamus in mice
    Koshi Murata, Tomoki Kinoshita, Yugo Fukazawa, Kenta Kobayashi, Kazuto Kobayashi, Kazunari Miyamichi, Hiroyuki Okuno, Haruhiko Bito, Yoshio Sakurai, Masahiro Yamaguchi, Kensaku Mori, Hiroyuki Manabe
    Scientific Reports, Springer Science and Business Media LLC, 9(1)7132 - 7132, Dec. 2019, English, Research paper (scientific journal)
  • Opposing Roles of Dopamine Receptor D1- and D2-Expressing Neurons in the Anteromedial Olfactory Tubercle in Acquisition of Place Preference in Mice
    Koshi Murata, Tomoki Kinoshita, Yugo Fukazawa, Kenta Kobayashi, Akihiro Yamanaka, Takatoshi Hikida, Hiroyuki Manabe, Masahiro Yamaguchi
    Frontiers in Behavioral Neuroscience, Frontiers Media SA, 13, 15 Mar. 2019, Research paper (scientific journal)
  • CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.
    Kosuke Okuda, Shizuka Kobayashi, Masahiro Fukaya, Aya Watanabe, Takuto Murakami, Mai Hagiwara, Tempei Sato, Hiroe Ueno, Narumi Ogonuki, Sayaka Komano-Inoue, Hiroyuki Manabe, Masahiro Yamaguchi, Atsuo Ogura, Hiroshi Asahara, Hiroyuki Sakagami, Masashi Mizuguchi, Toshiya Manabe, Teruyuki Tanaka
    Neurobiology of disease, 106158 - 170, Oct. 2017, English, Research paper (scientific journal)
  • Temporal coordination of olfactory cortex sharp-wave activity with up- and downstates in the orbitofrontal cortex during slow-wave sleep
    Naomi Onisawa, Hiroyuki Manabe, Kensaku Mori
    JOURNAL OF NEUROPHYSIOLOGY, AMER PHYSIOLOGICAL SOC, 117(1)123 - 135, Jan. 2017, English, Research paper (scientific journal)
  • Possible functional role of olfactory subsystems in monitoring inhalation and exhalation
    Kensaku Mori, Hiroyuki Manabe, Kimiya Narikiyo
    FRONTIERS IN NEUROANATOMY, FRONTIERS RESEARCH FOUNDATION, 8107 , Sep. 2014, English
  • Top-down inputs from the olfactory cortex in the postprandial period promote elimination of granule cells in the olfactory bulb
    Sayaka Komano-Inoue, Hiroyuki Manabe, Mizuho Ota, Ikue Kusumoto-Yoshida, Takeshi K. Yokoyama, Kensaku Mori, Masahiro Yamaguchi
    EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, 40(5)2724 - 2733, Sep. 2014, English
  • Unique characteristics of the olfactory system
    Kensaku Mori, Hiroyuki Manabe
    The Olfactory System: From Odor Molecules to Motivational Behaviors, Springer Japan, 1 - 18, 01 Feb. 2014, English
  • Parallel tufted cell and mitral cell pathways from the olfactory bulb to the olfactory cortex
    Shin Nagayama, Kei M. Igarashi, Hiroyuki Manabe, Kensaku Mori
    The Olfactory System: From Odor Molecules to Motivational Behaviors, Springer Japan, 133 - 160, 01 Feb. 2014, English
  • Sharp wave-associated synchronized inputs from the piriform cortex activate olfactory tubercle neurons during slow-wave sleep
    Kimiya Narikiyo, Hiroyuki Manabe, Kensaku Mori
    JOURNAL OF NEUROPHYSIOLOGY, AMER PHYSIOLOGICAL SOC, 111(1)72 - 81, Jan. 2014, English, Research paper (scientific journal)
  • Sniff rhythm-paced fast and slow gamma-oscillations in the olfactory bulb: relation to tufted and mitral cells and behavioral states
    Hiroyuki Manabe, Kensaku Mori
    JOURNAL OF NEUROPHYSIOLOGY, AMER PHYSIOLOGICAL SOC, 110(7)1593 - 1599, Oct. 2013, English, Research paper (scientific journal)
  • Reorganization of neuronal circuits of the central olfactory system during postprandial sleep
    Masahiro Yamaguchi, Hiroyuki Manabe, Koshi Murata, Kensaku Mori
    FRONTIERS IN NEURAL CIRCUITS, FRONTIERS RESEARCH FOUNDATION, 7132 , Aug. 2013, English
  • Olfactory consciousness and gamma oscillation couplings across the olfactory bulb, olfactory cortex, and orbitofrontal cortex.
    Kensaku Mori, Hiroyuki Manabe, Kimiya Narikiyo, Naomi Onisawa
    Frontiers in psychology, 4743 - 743, 2013, English, Research paper (scientific journal)
  • Elimination of Adult-Born Neurons in the Olfactory Bulb Is Promoted during the Postprandial Period
    Takeshi K. Yokoyama, Daisuke Mochimaru, Koshi Murata, Hiroyuki Manabe, Ko Kobayakawa, Reiko Kobayakawa, Hitoshi Sakano, Kensaku Mori, Masahiro Yamaguchi
    NEURON, CELL PRESS, 71(5)883 - 897, Sep. 2011, English, Research paper (scientific journal)
  • Olfactory Cortex Generates Synchronized Top-Down Inputs to the Olfactory Bulb during Slow-Wave Sleep
    Hiroyuki Manabe, Ikue Kusumoto-Yoshida, Mizuho Ota, Kensaku Mori
    JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, 31(22)8123 - 8133, Jun. 2011, English, Research paper (scientific journal)
  • 徐波睡眠時に起こる、嗅皮質、嗅球での鋭波発生メカニズムの解析(Neuronal circuits responsible for the generation of olfactory cortex and olfactory bulb sharp waves during slow-wave sleep)
    眞部 寛之, 楠本 郁恵[吉田], 太田 瑞穂, 森 憲作
    神経化学, 日本神経化学会, 49(2-3)507 - 507, Aug. 2010, English
  • 嗅皮質の鋭波は眼窩前頭皮質や扁桃体と連動しながら徐波睡眠時に起こる(Olfactory cortex sharp waves occur during slow wave sleep in a coordinated manner with orbitofrontal cortex and amygdala)
    太田 瑞穂, 真部 寛之, 楠本 郁恵[吉田], 森 憲作
    神経化学, 日本神経化学会, 49(2-3)731 - 731, Aug. 2010, English
  • 嗅皮質は、徐波睡眠時に鋭波を発生する(Olfactory cortex generates sharp waves during slow-wave sleep)
    楠本 郁恵[吉田], 眞部 寛之, 太田 瑞穂, 森 憲作
    神経化学, 日本神経化学会, 49(2-3)731 - 731, Aug. 2010, English
  • Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein
    Tomohiro Ueda, Hiroyuki Manabe, Keizo Tokuhiro, Mika Hirose, Yasuhiro Matsuoka, Yasushi Miyagawa, Akira Tsujimura, Kyoko Fujita, Morimasa Wada, Akihiko Okuyama, Yoshitake Nishimune, Hiromitsu Tanaka
    INTERNATIONAL JOURNAL OF UROLOGY, WILEY-BLACKWELL PUBLISHING, INC, 16(7)639 - 646, Jul. 2009, English, Research paper (scientific journal)
  • Cloning and characterization of a mouse spergen-1 localized in sperm mitochondria
    Y Matsuoka, N Iguchi, K Kitamura, H Nishimura, H Manabe, Y Miyagawa, M Koga, K Matsumiya, A Okuyama, H Tanaka, Y Nishimune
    INTERNATIONAL JOURNAL OF ANDROLOGY, BLACKWELL PUBLISHING LTD, 27(3)152 - 160, Jun. 2004, English, Research paper (scientific journal)

Misc

  • Analysis of the neuronal circuits of odor-induced eating behavior in mice
    眞部寛之, 村田航志
    浦上財団研究報告書, 2579‐83 , 27 Mar. 2018, Japanese
  • 嗅皮質鋭波中のニューロン再活性化の解析
    眞部 寛之
    上原記念生命科学財団研究報告集, 上原記念生命科学財団, 271 - 5, Dec. 2013, Japanese
  • The olfactory cortex internally generates exhalation-phased active state without olfactory sensory input
    Kimiya Narikiyo, Hiroyuki Manabe, Yoshihiro Yoshihara, Kensaku Mori
    CHEMICAL SENSES, OXFORD UNIV PRESS, 41(9)E148 - E148, Nov. 2016, English, Research paper, summary (international conference)
  • Temporally-coordinated communication between olfactory cortex and orbitofrontal cortex during slow-wave sleep in rats
    Hiroyuki Manabe, Naomi Onisawa, Kensaku Mori
    CHEMICAL SENSES, OXFORD UNIV PRESS, 41(9)E151 - E152, Nov. 2016, English, Research paper, summary (international conference)
  • How can the brain encode unlimited amount of memory? - temporary cell assemblies in hippocampus
    Sakurai, Yoshio, Manabe, Hiroyuki, Hirokawa, Junya
    INTERNATIONAL JOURNAL OF PSYCHOLOGY, ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 51874 - 874, Jul. 2016, English, Research paper, summary (international conference)
  • Synchronized top-down inputs from the olfactory cortex participate in the cell death of adult-born neurons in the olfactory bulb
    Sayaka Komano, Hiroyuki Manabe, Mizuho Ota, Ikue Kusumoto-Yoshida, Takeshi Yokoyama, Kensaku Mori, Masahiro Yamaguchi
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 71E237 - E237, 2011, English, Research paper, summary (international conference)
  • Olfactory cortex generates sharp waves during slow-wave sleep
    Ikue Kusumoto-Yoshida, Hiroyuki Manabe, Mizuho Ota, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 68E390 - E390, 2010, English, Research paper, summary (international conference)
  • Neuronal circuits responsible for the generation of olfactory cortex and olfactory bulb sharp waves during slow-wave sleep
    Hiroyuki Manabe, Ikue Kusumoto-Yoshida, Mizuho Ota, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 68E98 - E98, 2010, English, Research paper, summary (international conference)
  • Olfactory cortex sharp waves occur during slow wave sleep in a coordinated manner with orbitofrontal cortex and amygdala
    Mizuho Ota, Hiroyuki Manabe, Ikue Kusumoto-Yoshida, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 68E390 - E390, 2010, English, Research paper, summary (international conference)
  • Neocortex-independent slow wave activity in the olfactory cortex: A study with urethane anesthetized rats
    Hideki Kashiwadani, Hiroyuki Manabe, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 61S105 - S105, 2008, English, Research paper, summary (international conference)
  • Neocortex-independent slow-wave activity in the olfactory cortex: A study with freely behaving rats
    Hiroyuki Manabe, Hideki Kashiwadani, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 61S178 - S178, 2008, English, Research paper, summary (international conference)
  • Behavioral state-dependent simultaneously change between the respiratory pattern and information processing mode in hippocampus
    Hiroyuki Manabe, Kensaku Mori
    NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 58S167 - S167, 2007, English, Research paper, summary (international conference)

Conference Activities & Talks

  • 睡眠のグローバル制御とローカル制御 嗅覚系で食後徐波睡眠時に起こる鋭波とその機能
    眞部 寛之, 楠本 郁恵, 田, 駒野 清香, 太田 瑞穂, 森 憲作
    日本睡眠学会定期学術集会プログラム・抄録集, Jun. 2012, Japanese
  • 嗅皮質は、徐波睡眠時に鋭波を発生する(Olfactory cortex generates sharp waves during slow-wave sleep)
    楠本 郁恵, 吉田, 眞部 寛之, 太田 瑞穂, 森 憲作
    神経化学, Aug. 2010, English
  • 徐波睡眠時に起こる、嗅皮質、嗅球での鋭波発生メカニズムの解析(Neuronal circuits responsible for the generation of olfactory cortex and olfactory bulb sharp waves during slow-wave sleep)
    眞部 寛之, 楠本 郁恵, 田, 太田 瑞穂, 森 憲作
    神経化学, Aug. 2010, English
  • Behavioral state-dependent simultaneously change between the respiratory pattern and information processing mode in hippocampus
    Manabe Hiroyuki, Mori Kensaku
    NEUROSCIENCE RESEARCH, 2007