TAHARA Yoshiro
Faculty of Science and Engineering Department of Chemical Engineering and Materials Science
Associate Professor
Last Updated :2021/10/23

Researcher Profile and Settings

Research Interests

  • Transdermal delivery
  • Cancer immunotherapy
  • Gel
  • Tissue engineering
  • Emulsion
  • Polysaccharides
  • Nanotechnology
  • Vaccine
  • Cancer
  • Biomaterials
  • Drug Delivery System

Research Areas

  • Nanotechnology/Materials/Biochemistry
  • Nanotechnology/Materials/Polymer chemistry
  • Life sciences/Biomaterials
  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering)/Applied biofunctional and bioprocess engineering

Academic & Professional Experience

  • Associate professor, Faculty of science and engineering, Doshisha University, 2019/04 - Today
  • Research Assistant Professor, Department of Applied Chemistry, Kyushu University, Japan, 2017/03 - 2019/03
  • Post-doctoral Researcher, JST-ERATO Akiyoshi Bio-Nanotransporter Project, Japan, 2012/04 - 2017/02
  • Post-doctoral Researcher, Department of Polymer Chemistry, Kyoto University, Japan. (Advisor: Prof. Kazunari Akiyoshi), 2012/04 - 2017/02
  • Japan Society for the Promotion of Science (JSPS) Research Fellow (DC1), 2009/04 - 2012/03

Education

  • Kyushu University, Japan. (Advisor: Prof. Masahiro Goto & Prof. Noriho Kamiya), Department of Applied Chemistry, 2007/04 - 2012/03
  • Kyushu University, Japan (Advisor: Prof. Masahiro Goto & Prof. Noriho Kamiya), Department of Applied Chemistry, 2003/04 - 2007/03

Academic Degrees

  • Ph.D., Kyushu University

Awards & Honors

  • Best Oral Presenter Award for Young Researchers, Japan Society of Drug Delivery System, Japan
    Jun. 2011
  • Best Poster Presenter Award for Young Researchers, Division of Biochemical Enginnering, The Society of Chemical Engineers, Japan
    Sep. 2010
  • Best Poster Presenter Award for Young Researchers, Japan Society of Drug Delivery System, Japan
    Jul. 2009
  • Best Poster Presenter Award for Young Researchers, Division of Biochemical Enginnering, The Society of Chemical Engineers, Japan
    Sep. 2007
  • Best Oral Presenter Award for Young Researchers, The Society of Chemical Engineers, Japan
    Jul. 2007

Published Papers

  • PEER REVIEWED PUBLICTIONS
    Dec. 2021
  • Solid-in-oil nanodispersions as a novel delivery system to improve the oral bioavailability of bisphosphate, risedronate sodium
    Yanting Hou, Hongyu Piao, Yoshiro Tahara, Shouhong Qin, Jingying Wang, Qingliang Kong, Meijuan Zou, Gang Cheng, Masahiro Goto
    European Journal of Pharmaceutical Sciences, Elsevier BV, 155(1)105521 - 105521, Dec. 2020, Research paper (scientific journal)
  • In Vivo Regeneration of Large Bone Defects by Cross-Linked Porous Hydrogel: A Pilot Study in Mice Combining Micro Tomography, Histological Analyses, Raman Spectroscopy and Synchrotron Infrared Imaging
    Tetsuya Adachi, Francesco Boschetto, Nao Miyamoto, Toshiro Yamamoto, Elia Marin, Wenliang Zhu, Narisato Kanamura, Yoshiro Tahara, Kazunari Akiyoshi, Osam Mazda, Ichiro Nishimura, Giuseppe Pezzotti
    Materials, MDPI AG, 13(19)4275 - 4275, 25 Sep. 2020, English, Research paper (scientific journal)
  • Lactic Acid Permeation through Deep Eutectic Solvents-Based Polymer Inclusion Membranes
    Michiaki Matsumoto, Sae Takemori, Yoshiro Tahara
    Membranes, MDPI AG, 10(9)244 - 244, 19 Sep. 2020, Research paper (scientific journal)
  • Biocompatible Ionic Liquid Enhances Transdermal Antigen Peptide Delivery and Preventive Vaccination Effect', Molecular Pharmaceutics
    Yoshiro Tahara, Kaho Morita, Rie Wakabayashi, Noriho Kamiya, Masahiro Goto
    Molecular Pharmaceutics, 17(10)3845 - 3856, 09 Sep. 2020
  • Choline and amino acid based biocompatible ionic liquid mediated transdermal delivery of the sparingly soluble drug acyclovir
    Md. Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto
    International Journal of Pharmaceutics, Elsevier BV, 582119335 - 119335, 30 May 2020, Research paper (scientific journal)
  • Solid-in-Oil Nanodispersions for Transcutaneous Immunotherapy of Japanese Cedar Pollinosis
    Qingliang Kong, Momoko Kitaoka, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    Pharmaceutics, 12(3)240 , 07 May 2020
  • Extraction of Rare Earth Metal Ions with an Undiluted Hydrophobic Pseudoprotic Ionic Liquid
    Michiaki Matsumoto, Takuya Yamaguchi, Yoshiro Tahara
    Metals, MDPI AG, 10(4)502 - 502, 11 Apr. 2020, Research paper (scientific journal)
  • A Solid-in-Oil Nanodispersion System for Transcutaneous Immunotherapy of Cow’s Milk Allergies
    Momoko Kitaoka, Wei Xiao, Qingliang Kong, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    Pharmaceutics, 12(3)205 , Feb. 2020
  • Ionic liquids with N-methyl-2-pyrrolidonium cation as an enhancer for topical drug delivery: Synthesis, characterization, and skin-penetration evaluation
    Rahman Md. Moshikur, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto
    Journal of Molecular Liquids, 1112166 , Feb. 2020
  • Transcutaneous Cancer Vaccine Using a Reverse Micellar Antigen Carrier
    Shuto Kozaka, Yoshiro Tahara, Rie Wakabayashi, Tahakhiro, Nakata, Taro Ueda, Noriho Kamiya, Masahiro Goto
    Molecular Pharmaceutics, 17(2)645 - 655, Dec. 2019
  • Solid-in-oil nanodispersions for intranasal vaccination: Enhancement of mucosal and systemic immune responses
    Qingliang Kong, Momoko Kitaoka, Yoshiro Tahara, Rie Wakabayashi, Noriho Kamiya, Masahiro Goto
    International Journal of Pharmaceutics, 572(15)118777 , Dec. 2019
  • Transcutaneous delivery of immunomodulating pollen extract-galactomannan conjugate by solid-in-oil nanodispersions for pollinosis immunotherapy
    Qingliang Kong, Kouki Higasijima, Rie Wakabayashi, Yoshiro Tahara, Momoko Kitaoka, Hiroki Obayashi, Yanting Hou, Noriho Kamiya, Masahiro Goto
    Pharmaceutics, 11(11)563 , Oct. 2019
  • Development of a novel ionic liquid-curcumin complex to enhance its solubility, stability, and activity
    Md. Raihan Chowdhury, Rahman Md Moshikur, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto
    Chemical Communications, 557737 - 7740, Jun. 2019
  • In vivo biocompatibility, pharmacokinetics, antitumor efficacy, and hypersensitivity evaluation of ionic liquid-mediated paclitaxel formulations
    Md. Raihan Chowdhury, Rahman Md Moshikur, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto
    International Journal of Pharmaceutics, 565219 - 226, May 2019
  • Synthesis and characterization of choline–fatty-acid-based ionic liquids: A new biocompatible surfactant
    Md Korban Ali, Rahman Md Moshikur, Rie Wakabayashi, Yoshiro Tahara, Muhammad Moniruzzaman, Noriho Kamiya, Masahiro Goto
    Journal of Colloid and Interface Science, 551(1)72 - 80, May 2019
  • Transcutaneous Codelivery of Tumor Antigen and Resiquimod in Solid-in-Oil Nanodispersions Promotes Antitumor Immunity
    Rie Wakabayashi, Hidetoshi Kono, Shuto Kozaka, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    ACS Biomaterials Science & Engineering, 5(5)2297 - 2306, Apr. 2019
  • Ionic liquids with methotrexate moieties as a potential anticancer prodrug: Synthesis, characterization and solubility evaluation
    Rahman Md. Moshikur, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara, Muhammad Moniruzzaman, Masahiro Goto
    Journal of Molecular Liquids, 278(15)226 - 233, Mar. 2019
  • Antigen Delivery Targeting Tumor-Associated Macrophages Overcomes Tumor Immune Resistance
    Daisuke Muraoka, Naohiro Seo, Tae Hayashi, Yoshiro Tahara, Keisuke Fujii, Isao Tawara, Yoshihiro Miyahara, Kana Okamori, Hideo Yagita, Seiya Imoto, Rui Yamaguchi, Mitsuhiro Komura, Satoru Miyano, Masahiro Goto, Shin-ichi Sawada, Akira Asai, Hiroaki Ikeda, Kazunari Akiyoshi, Naozumi Harada, Hiroshi Shiku
    Journal of Clinical Investigation, 129(3)1278 - 1294, Jan. 2019, English
  • Structural effects and lymphocyte activation properties of self-assembled polysaccharide nanogels for effective antigen delivery
    Risako Miura, Yoshiro Tahara, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
    Scientific Reports, 816464 - 16472, Nov. 2018
  • Nanogel tectonic porous 3D scaffold for direct reprogramming fibroblasts into osteoblasts and bone regeneration
    Yoshiki Sato, Kenta Yamamoto, Satoshi Horiguchi, Yoshiro Tahara, Kei Nakai, Shin-ichiro Kotani, Fumishige Oseko, Giuseppe Pezzotti, Toshiro Yamamoto, Tsunao Kishida, Narisato Kanamura, Kazunari Akiyoshi, Osam Mazda
    Scientific Reports, 815824 - 15833, Oct. 2018
  • Ionic-Liquid-Based Paclitaxel Preparation: A New Potential Formulation for Cancer Treatment
    Md. Raihan Chowdhury, Rahman, Md. Moshikur, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto
    Molecular Pharmaceutics, 15(6)2484 - 2488, May 2018
  • Solid-in-Oil Peptide Nanocarriers for Transcutaneous Cancer Vaccine Delivery against Melanoma
    Rie Wakabayashi, Masato Sakuragi, Shuto Kozaka, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    Molecular Pharmaceutics, 15(3)955 - 961, Feb. 2018
  • Activated CD8+ T Cell Extracellular Vesicles Prevent Tumour Progression by Targeting of Lesional Mesenchymal Cells
    Naohiro Seo, Yoshitaka Shirakura, Yoshiro Tahara, Fumiyasu Momose, Naozumi Harada, Hiroaki Ikeda, Kazunari Akiyoshi, Hiroshi Shiku
    Nature Communications, 9(0)435 , Jan. 2018
  • Preparation of Multiple Emulsions to Depress the Rlease of Drugs and Enhanced Permeation Effect in Transdermal Delivery
    Yuko Abe, Yoshiro Tahara, Rie Wakabayashi, Noriho Kamiya, Masahiro Goto
    Membrane, 38(2)92 - 96, Mar. 2013
  • Oil Gel Sheets Utilizing Solid–in–Oil Technique
    Asami Funatsu, Yoshiro Tahara, Sakurako Yamanaka, Masahiro Goto
    Membrane, 36(2)57 - 62, Mar. 2011
  • A transdermal delivery system of an ascorbic acid derivative utilizing solid-in-oil technique
    Aiko Okuma, Hongyu Piao, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    Membrane, 34(4)227 - 232, Jul. 2009
  • Effects of imprinting and water activity on transesterification and thermostability with lipases in ionic liquid
    M. Matsumoto, K. Nakao, Y. Tahara
    Chemical and Biochemical Engineering Quarterly, (1)57 - 63, 2021, Research paper (scientific journal)
  • Extraction of proteins with aqueous two-phase systems formed by protic ionic liquids and inorganic salts
    Michiaki Matsumoto, Fumiya Shinji, Yoshiro Tahara
    Solvent Extraction Research and Development, 28(2)141 - 148, 2021, Research paper (scientific journal)
  • Permeation of Phenylalanine through Polymer Inclusion Membrane Containing Bi-functional Ionic Liquid
    Michiaki Matsumoto, Kei Inoue, Yoshiro Tahara
    Solvent Extraction Research and Development, 27(2)143 - 147, 2020, Research paper (scientific journal)
  • Osteogenic response of mesenchymal progenitor cells to natural polysaccharide nanogel and atelocollagen scaffolds: A spectroscopic study
    Satoshi Horiguchi, Tetsuya Adachi, Alfredo Rondinella, Francesco Boschetto, Elia Marin, Wenliang Zhu, Yoshiro Tahara, Toshiro Yamamoto, Narisato Kanamura, Kazunari Akiyoshi, Giuseppe Pezzotti, Osam Mazda
    Materials Science and Engineering C, 991325 - 1340, Jun. 2019, Research paper (scientific journal)
  • Characterization and cytotoxicity evaluation of biocompatible amino acid esters used to convert salicylic acid into ionic liquids
    Rahman Md. Moshikur, Md. Raihan Chowdhury, Rie Wakabayashi, Yoshiro Tahara, Muhammad Moniruzzaman, Masahiro Goto
    International Journal of Pharmaceutics, Elsevier B.V., 546(1-2)31 - 38, 30 Jul. 2018, English, Research paper (scientific journal)
  • Mechanistic investigation of transcutaneous protein delivery using solid-in-oil nanodispersion: A case study with phycocyanin.
    Safrina Dyah Hardiningtyas, Rie Wakabayashi, Momoko Kitaoka, Yoshiro Tahara, Kosuke Minamihata, Masahiro Goto, Noriho Kamiya
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 127(0)44 - 50, Jun. 2018, English, Research paper (scientific journal)
  • Genipin-stabilized caseinatehitosan nanoparticles for enhanced stability and anti-cancer activity of curcumin
    Muhamad Alif Razi, Rie Wakabayashi, Yoshiro Tahara, Masahiro Goto, Noriho Kamiya
    Colloids and Surfaces B: Biointerfaces, Elsevier B.V., 164(1)308 - 315, 01 Apr. 2018, English, Research paper (scientific journal)
  • Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells
    Asako Shimoda, Yoshiro Tahara, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, 491(3)701 - 707, Sep. 2017, English, Research paper (scientific journal)
  • Self-Assembled Nanogels of Cholesterol-Bearing Hydroxypropyl Cellulose: A Thermoresponsive Building Block for Nanogel Tectonic Materials
    Yoshiro Tahara, Mizuki Sakiyama, Shigeo Takeda, Tomoki Nishimura, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
    LANGMUIR, AMER CHEMICAL SOC, 32(47)12283 - 12289, Nov. 2016, English, Research paper (scientific journal)
  • Current advances in self-assembled nanogel delivery systems for immunotherapy
    Yoshiro Tahara, Kazunari Akiyoshi
    ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER SCIENCE BV, 95(1)65 - 76, Dec. 2015, English
  • Nanocarrier-Integrated Microspheres: Nanogel Tectonic Engineering for Advanced Drug-Delivery Systems
    Yoshiro Tahara, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
    ADVANCED MATERIALS, WILEY-V C H VERLAG GMBH, 27(34)5080 - +, Sep. 2015, English, Research paper (scientific journal)
  • Effective CpG DNA delivery using amphiphilic cycloamylose nanogels
    Y. Tahara, J. Yasuoka, S. Sawada, Y. Sasaki, K. Akiyoshi
    BIOMATERIALS SCIENCE, ROYAL SOC CHEMISTRY, 3(2)256 - 264, 2015, English, Research paper (scientific journal)
  • Nanogel-Based Immunologically Stealth Vaccine Targets Macrophages in the Medulla of Lymph Node and Induces Potent Antitumor Immunity
    Daisuke Muraoka, Naozumi Harada, Tae Hayashi, Yoshiro Tahara, Fumiyasu Momose, Shin-ichi Sawada, Sada-atsu Mukai, Kazunari Akiyoshi, Hiroshi Shiku
    ACS NANO, AMER CHEMICAL SOC, 8(9)9209 - 9218, Sep. 2014, English, Research paper (scientific journal)
  • Sucrose laurate-enhanced transcutaneous immunization with a solid-in-oil nanodispersion
    Momoko Kitaoka, Kana Imamura, Yuya Hirakawa, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    MEDCHEMCOMM, ROYAL SOC CHEMISTRY, 5(1)20 - 24, 2014, English, Research paper (scientific journal)
  • Needle-free immunization using a solid-in-oil nanodispersion enhanced by a skin-permeable oligoarginine peptide
    Momoko Kitaoka, Kana Imamura, Yuya Hirakawa, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER SCIENCE BV, 458(2)334 - 339, Dec. 2013, English, Research paper (scientific journal)
  • S/O-nanodispersion electrospun fiber mesh effective for sustained release of healthy plasmid DNA with the structural and functional integrity
    Tatsuya Okuda, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto, Satoru Kidoaki
    JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, TAYLOR & FRANCIS LTD, 24(10)1277 - 1290, Jul. 2013, English, Research paper (scientific journal)
  • Cationic amphiphilic polysaccharide nanoballs: protein stabilization and intracellular delivery by nano-encapsulation
    Haruko Takahashi, Yoshiro Tahara, Shin-ichi Sawada, Kazunari Akiyoshi
    BIOMATERIALS SCIENCE, ROYAL SOC CHEMISTRY, 1(8)842 - 849, 2013, English, Research paper (scientific journal)
  • Nanogel bottom-up gel biomaterials for protein delivery: Photopolymerization of an acryloyl-modified polysaccharide nanogel macromonomer
    Yoshiro Tahara, Satoshi Kosuge, Shin-Ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
    Reactive and Functional Polymers, 73(7)958 - 964, 2013, English, Research paper (scientific journal)
  • Transdermal delivery of insulin using a solid-in-oil nanodispersion enhanced by arginine-rich peptides
    Yoshiro Tahara, Shota Honda, Noriho Kamiya, Masahiro Goto
    MEDCHEMCOMM, ROYAL SOC CHEMISTRY, 3(12)1496 - 1499, Dec. 2012, English, Research paper (scientific journal)
  • Solid-in-oil dispersion: A novel core technology for drug delivery systems
    Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER SCIENCE BV, 438(1-2)249 - 257, Nov. 2012, English
  • A novel double-coating carrier produced by solid-in-oil and solid-in-water nanodispersion technology for delivery of genes and proteins into cells
    Yoshiro Tahara, Takeshi Kaneko, Riki Toita, Chiharu Yoshiyama, Takuya Kitaoka, Takuro Niidome, Yoshiki Katayama, Noriho Kamiya, Masahiro Goto
    JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE BV, 161(3)713 - 721, Aug. 2012, English, Research paper (scientific journal)
  • A Solid-in-Oil Dispersion of Gold Nanorods Can Enhance Transdermal Protein Delivery and Skin Vaccination
    Dakrong Pissuwan, Keisuke Nose, Ryohsuke Kurihara, Kenji Kaneko, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto, Yoshiki Katayama, Takuro Niidome
    SMALL, WILEY-V C H VERLAG GMBH, 7(2)215 - 220, Jan. 2011, English, Research paper (scientific journal)
  • Ionic liquid-in-oil microemulsion as a potential carrier of sparingly soluble drug: Characterization and cytotoxicity evaluation
    Muhammad Moniruzzaman, Miki Tamura, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER SCIENCE BV, 400(1-2)243 - 250, Nov. 2010, English, Research paper (scientific journal)
  • Transcutaneous immunization by a solid-in-oil nanodispersion
    Yoshiro Tahara, Kenichi Namatsu, Noriho Kamiya, Masayori Hagimori, Seitaro Kamiya, Masayuki Arakawa, Masahiro Goto
    CHEMICAL COMMUNICATIONS, ROYAL SOC CHEMISTRY, 46(48)9200 - 9202, 2010, English, Research paper (scientific journal)
  • Ionic liquid-assisted transdermal delivery of sparingly soluble drugs
    Muhammad Moniruzzaman, Yoshiro Tahara, Miki Tamura, Noriho Kamiya, Masahiro Goto
    CHEMICAL COMMUNICATIONS, ROYAL SOC CHEMISTRY, 46(9)1452 - 1454, 2010, English, Research paper (scientific journal)
  • A solid-in-oil nanodispersion for transcutaneous protein delivery
    Yoshiro Tahara, Shota Honda, Noriho Kamiya, Hongyu Piao, Akihiko Hirata, Eiji Hayakawa, Takeru Fujii, Masahiro Goto
    JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE BV, 131(1)14 - 18, Oct. 2008, English, Research paper (scientific journal)
  • Design and in vivo evaluation of solid-in-oil suspension for oral delivery of human growth hormone
    Hiromu Yoshiura, Yoshiro Tahara, Masakazu Hashida, Noriho Kamiya, Akihiko Hirata, Takeru Fujii, Masahiro Goto
    BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, 41(2)106 - 110, Sep. 2008, English, Research paper (scientific journal)

Misc

  • BOOK CHAPTERS etc
    Nov. 2019
  • S/O技術によるペプチドの経皮吸収
    Yoshiro Tahara, Masahiro Goto
    COSMETIC STAGE, 13(2)48 - 52, Dec. 2018
  • Solid-in-Oil(S/O)化技術と経皮ワクチンへの応用
    Yoshiro Tahara, Masahiro Goto
    PHARM TECH JAPAN, 34(14)199 - 202, Nov. 2018
  • イオン液体を用いたDDSと経皮デリバリーへの応用の現状
    Yoshiro Tahara, Masahiro Goto
    Drug Delivery System, 33(4)303 - 310, Sep. 2018
  • S/O 技術による皮膚浸透促進と化粧品開発
    Yoshiro Tahara, Masahiro Goto
    月刊ファインケミカル, 47(3)pp.38 - 44, Mar. 2018
  • 機能性自己組織化多糖ナノゲルの設計とバイオメディカル応用
    澤田晋一, 澤田晋一, 田原義朗, 向井貞篤, 向井貞篤, 佐々木善浩, 秋吉一成, 秋吉一成
    高分子学会予稿集(CD-ROM), 66(2)ROMBUNNO.2O07 , 06 Sep. 2017, Japanese
  • 微粒子等を用いたドラッグデリバリーシステム
    田原義朗, 秋吉一成
    動物用ワクチンとバイオ医薬品, pp.248 - 251, Jul. 2017
  • 経皮吸収製剤における最新のDDS技術
    田原義朗, 後藤雅宏
    DDS先端技術の先端バイオ医薬品への応用開発, 8(1)pp.404 - 409, Jun. 2017
  • Transdermal protein delivery and immunization by a solid-in-oil nanodispersion technique
    Yoshiro Tahara, Masahiro Goto
    Drug Delivery System, Japan Society of Drug Delivery System, 32(3)176 - 183, 2017, Japanese, Book review, literature introduction, etc.
  • 自己組織化ナノゲルによるDDS開発
    田原義朗, 秋吉一成
    月刊ファインケミカル, 45(11)pp.25 - 32, Nov. 2016
  • 物理架橋ナノゲルの調製とDDS応用
    田原義朗, 秋吉一成
    DDSキャリア作製プロトコル集, pp.124 - 130, Aug. 2015
  • Pullulan
    Yoshiro Tahara, Kazunari Akiyoshi
    Encyclopedia of polymeric nanomaterials, 2121 - 2129, Jun. 2015
  • ナノゲル基盤材料によるタンパク質医薬の徐放技術とその応用
    田原義朗, 秋吉一成
    遺伝子医学MOOK別冊 – ここまで広がるドラッグ徐放技術の最前線 –, pp.124 - 130, Mar. 2013
  • S/O®技術を用いたタンパク性医薬品の経皮吸収改善と経皮免疫への応用
    後藤雅宏, 田原義朗
    遺伝子医学MOOK別冊 – ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用 –, pp.141 - 147, Jun. 2011
  • タンパク質の経皮デリバリーは本当に可能か?
    後藤雅宏, 田原義朗
    化学, 66pp.54 - 57, May 2011
  • 新規カチオン性ダブルコーティング型キャリアによる遺伝子デリバリー
    田原義朗, 金子丈志, 戸井田力, 神谷典穂, 新留琢郎, 片山佳樹, 後藤雅宏
    日本バイオマテリアル学会大会予稿集, 32nd192 , 29 Nov. 2010, Japanese
  • 独自のエマルション化技術を利用した新規ダブルコーティング型キャリアの開発
    田原義朗, 金子丈志, 戸井田力, 神谷典穂, 新留琢郎, 片山佳樹, 後藤雅宏
    Drug Deliv Syst, 25(3)302 , 28 May 2010, Japanese
  • 新規ダブルコーティング型キャリアの開発と非ウイルス性遺伝子デリバリーへの応用
    田原義朗, 金子丈志, 戸井田力, 神谷典穂, 新留琢郎, 片山佳樹, 後藤雅宏
    Drug Deliv Syst, 25(3)334 , 28 May 2010, Japanese
  • S/O化技術の魅力と新しい経皮薬物送達システム実現の可能性
    田原義朗, 神谷典穂, 後藤雅宏
    PHARM TECH JAPAN, 25pp.1409 - 1414, Jun. 2009
  • タンパク質の経皮デリバリーの実現
    田原義朗, 神谷典穂, 後藤雅宏
    バイオサイエンスとインダストリー, 67pp.68 - 70, Apr. 2009
  • Development and clarification of a novel transcutaneous protein delivery system and its mechanism by a solid-in-oil nanodispersion
    Yoshiro Tahara, Shota Honda, Noriho Kamiya, Masahiro Goto
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, 108S39 - S40, Nov. 2009, English, Research paper, summary (international conference)

Patents

  • 多孔質三次元細胞培養足場材料及びその製造方法
    佐藤良樹, 山本健太, 堀口智史, 田原義朗, 山本俊郎, 岸田綱郎, 秋吉一成, 松田修
    特願2018-158931
  • Crosslinked hydrophobized-polysaccharide nanogel particles and manufacturing method therefor
    Kazunari Akiyoshi, Yoshiro Tahara, Sadaatsu Mukai, Shinichi Sawada
    PCT/JP2014/059082
  • Water-soluble drug carrier and process for production thereof
    Masahiro Goto, Noriho Kamiya, Yoshiro Tahara
    PCT/JP2010/004021, Kyushu University, National University Corporation