Researcher Profile and Settings

researchmap

https://researchmap.jp/0922

Research funding number

70609122

Research Interests

• エネルギー代謝
• noncoding RNA
• Selenoprotein P
• 糖尿病

Research Areas

• Life sciences / Food sciences

Research Experience

• Doshisha University, Faculty of Life and Medical Sciences Department of Medical Life Systems, 准教授, 2024/04 - Today
• Doshisha University, Faculty of Life and Medical Sciences Department of Medical Life Systems, 助教, 2019/04 - 2024/03
• University of Miyazaki, 神経呼吸内分泌代謝学講座, 特任助教, 2018/10 - 2019/03
• University of Miyazaki, 神経呼吸内分泌代謝学講座, 博士研究員, 2017/04 - 2018/09
• Doshisha University, Office for Research Initiatives and Development, 特別研究員, 2013/04 - 2017/03
• Kyoto Prefectural University of Medicine, 循環器腎臓内科学, 博士研究員, 2010/04 - 2013/03
• Okayama University, 戦略的プログラム支援ユニット, 非常勤研究員, 2009/09 - 2010/03

Education

• Okayama University, Graduate School of Medicine , Dentistry and Pharmaceutical Sciences, 2005/04 - 2010/03
• Kyoto Prefectural University, 農学研究科博士前期課程, 2003/04 - 2005/03
• Gunma University, 工学部, 生物化学工学科, 1999/04 - 2003/03

Association Memberships

• 日本糖尿病学会
• 日本薬学会
• 日本酸化ストレス学会
• 日本生化学会
• 日本分子生物学会

Awards

• 学術奨励賞
  Jun. 2019, 日本酸化ストレス学会

Published Papers

• Mechanisms of Selenoprotein P translation regulation by long noncoding RNA
  Yuichiro Mita; Yukihiro Inenaga; Noriko Noguchi
  Metallomics Research, 5(1) rev19 - rev23, Feb. 2025
• Modifications of DJ-1 in which pI shifts to acidic in red blood cells a potential biomarker for Parkinson's disease at early stages.
  Kohei Matsuda; Yuichiro Mita; Kazumasa Saigoh; Yoshiro Saito; Noriko Noguchi
  Free radical research, 1 - 10, 22 Nov. 2024, Scientific journal
  

  DOI URL
• Ethanol enhances selenoprotein P expression via ERK-FoxO3a axis in HepG2 cells
  Jian Chen; Yuichiro Mita; Noriko Noguchi
  Journal of Clinical Biochemistry and Nutrition, The Society for Free Radical Research Japan, 75(2) 125 - 132, Sep. 2024, Scientific journal
  

  URLDOI URL
• The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
  Weidong Zhang; Ayako Miura; Md Moin Abu Saleh; Koichiro Shimizu; Yuichiro Mita; Ryota Tanida; Satoshi Hirako; Seiji Shioda; Valery Gmyr; Julie Kerr-Conte; Francois Pattou; Chunhuan Jin; Yoshikatsu Kanai; Kazuki Sasaki; Naoto Minamino; Hideyuki Sakoda; Masamitsu Nakazato
  Nature Communications, Springer Science and Business Media LLC, 14(1) 8158 , 09 Dec. 2023, Scientific journal
  

  URLDOI URL
• An efficient selenium transport pathway of selenoprotein P utilizing a high-affinity ApoER2 receptor variant and being independent of selenocysteine lyase
  Ayako Mizuno; Takashi Toyama; Atsuya Ichikawa; Naoko Sakai; Yuya Yoshioka; Yukina Nishito; Renya Toga; Hiroshi Amesaka; Takayuki Kaneko; Kotoko Arisawa; Ryouhei Tsutsumi; Yuichiro Mita; Shun-ichi Tanaka; Noriko Noguchi; Yoshiro Saito
  Journal of Biological Chemistry, Elsevier BV, 299(8) 105009 - 105009, Jul. 2023, Scientific journal
  

  DOI URL
• Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation
  Takayuki Kaneko; Yuichiro Mita; Kanako Nozawa-Kumada; Masana Yazaki; Mieko Arisawa; Etsuo Niki; Noriko Noguchi; Yoshiro Saito
  Free Radical Research, Informa UK Limited, 56(9-10) 677 - 690, 03 Jan. 2023, Scientific journal
  

  URLDOI URL
• Role of selenoprotein P expression in the function of pancreatic β cells: Prevention of ferroptosis-like cell death and stress-induced nascent granule degradation
  Nanako Kitabayashi; Shohei Nakao; Yuichiro Mita; Kotoko Arisawa; Takayuki Hoshi; Takashi Toyama; Kiyo-aki Ishii; Toshinari Takamura; Noriko Noguchi; Yoshiro Saito
  Free Radical Biology and Medicine, Elsevier BV, 183 89 - 103, Apr. 2022, Scientific journal
  

  DOI URL
• Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation
  Y Mita; R Uchida; S Yasuhara; K Kishi; T Hoshi; Y Matsuo; T Yokooji; Y Shirakawa; T Toyama; Y Urano; T Inada; N Noguchi; Y Saito
  Nucleic Acids Research, Oxford University Press (OUP), 49(12) 6893 - 6907, Jun. 2021, Scientific journal
  

  URLDOI URL
• Liver-expressed antimicrobial peptide 2 antagonizes the effect of ghrelin in rodents.
  Md Nurul Islam; Yuichiro Mita; Keisuke Maruyama; Ryota Tanida; Weidong Zhang; Hideyuki Sakoda; Masamitsu Nakazato
  The Journal of endocrinology, 244(1) 13 - 23, 01 Jan. 2020, Scientific journal
  

  DOI URL
• Impaired adaptation of energy intake induces severe obesity in aged mice on a high-fat diet.
  Okada T; Mita Y; Sakoda H; Nakazato M
  Physiological reports, 7(3) e13989 , Jan. 2019, Scientific journal
  

  DOI URL
• Analysis of peripheral ghrelin signaling via the vagus nerve in ghrelin receptor–restored GHSR-null mice
  Tadashi Okada; T.M. Zaved Waise; Koji Toshinai; Yuichiro Mita; Hideyuki Sakoda; Masamitsu Nakazato
  Neuroscience Letters, Elsevier Ireland Ltd, 681 50 - 55, 10 Aug. 2018, Scientific journal
  

  DOI URL
• Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin.
  Mita Y; Kataoka Y; Saito Y; Kashi T; Hayashi K; Iwasaki A; Imanishi T; Miyasaka T; Noguchi N
  Scientific reports, 8(1) 12056 , Aug. 2018
  

  DOI URL
• Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models
  Yuichiro Mita; Kaho Nakayama; Shogo Inari; Yukina Nishito; Yuya Yoshioka; Naoko Sakai; Kanade Sotani; Takahiro Nagamura; Yuki Kuzuhara; Kumi Inagaki; Miki Iwasaki; Hirofumi Misu; Masaya Ikegawa; Toshinari Takamura; Noriko Noguchi; Yoshiro Saito
  NATURE COMMUNICATIONS, 8(1) 1658 , Nov. 2017, Scientific journal
  

  DOI URL
• Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
  Hirofumi Misu; Hiroaki Takayama; Yoshiro Saito; Yuichiro Mita; Akihiro Kikuchi; Kiyo-aki Ishii; Keita Chikamoto; Takehiro Kanamori; Natsumi Tajima; Fei Lan; Yumie Takeshita; Masao Honda; Mutsumi Tanaka; Seiji Kato; Naoto Matsuyama; Yuya Yoshioka; Kaito Iwayama; Kumpei Tokuyama; Nobuhiko Akazawa; Seiji Maeda; Kazuhiro Takekoshi; Seiichi Matsugo; Noriko Noguchi; Shuichi Kaneko; Toshinari Takamura
  NATURE MEDICINE, 23(4) 508 - +, Apr. 2017, Scientific journal
  

  DOI URL
• (D)-Glutamate is metabolized in the heart mitochondria
  Makoto Ariyoshi; Masumi Katane; Kenji Hamase; Yurika Miyoshi; Maiko Nakane; Atsushi Hoshino; Yoshifumi Okawa; Yuichiro Mita; Satoshi Kaimoto; Motoki Uchihashi; Kuniyoshi Fukai; Kazunori Ono; Syuhei Tateishi; Daichi Hato; Ryoetsu Yamanaka; Sakiko Honda; Yohei Fushimura; Eri Iwai-Kanai; Naotada Ishihara; Masashi Mita; Hiroshi Homma; Satoaki Matoba
  SCIENTIFIC REPORTS, 7 43911 , Mar. 2017, Scientific journal
  

  DOI URL
• Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients
  Yoshiro Saito; Yoko Akazawa-Ogawa; Akihiro Matsumura; Kazumasa Saigoh; Sayoko Itoh; Kenta Sutou; Mayuka Kobayashi; Yuichiro Mita; Mototada Shichiri; Shin Hisahara; Yasuo Hara; Harutoshi Fujimura; Hiroyuki Takamatsu; Yoshihisa Hagihara; Yasukazu Yoshida; Takao Hamakubo; Susumu Kusunoki; Shun Shimohama; Noriko Noguchi
  SCIENTIFIC REPORTS, 6 30793 , Jul. 2016, Scientific journal
  

  DOI URL
• Genetic polymorphism at codon 546 of the human RAD17 contributes to the risk for esophageal squamous cell carcinoma.
  Yasuda Y; Sakai A; Ito S; Mita Y; Sonoyama T; Tanabe S; Shirakawa Y; Naomoto Y; Katayama H; Shimizu K
  International journal of molecular epidemiology and genetics, 7(1) 58 - 66, 2016, Scientific journal
• Enhancement of lipid peroxidation and its amelioration by vitamin E in a subject with mutations in the SBP2 gene
  Yoshiro Saito; Mototada Shichiri; Takashi Hamajima; Noriko Ishida; Yuichiro Mita; Shohei Nakao; Yoshihisa Hagihara; Yasukazu Yoshida; Kazuhiko Takahashi; Etsuo Niki; Noriko Noguchi
  JOURNAL OF LIPID RESEARCH, 56(11) 2172 - 2182, Nov. 2015, Scientific journal
  

  DOI URL
• An alpha-adrenergic agonist protects hearts by inducing Akt1-mediated autophagy
  Mikihiko Nakaoka; Eri Iwai-Kanai; Maki Katamura; Yoshifumi Okawa; Yuichiro Mita; Satoaki Matoba
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 456(1) 250 - 256, Jan. 2015, Scientific journal
  

  DOI URL
• Immunostaining of Oxidized DJ-1 in Human and Mouse Brains
  Yoshiro Saito; Tomohiro Miyasaka; Hiroyuki Hatsuta; Kazuko Takahashi-Niki; Kojiro Hayashi; Yuichiro Mita; Osamu Kusano-Arai; Hiroko Iwanari; Hiroyoshi Ariga; Takao Hamakubo; Yasukazu Yoshida; Etsuo Niki; Shigeo Murayama; Yasuo Ihara; Noriko Noguchi
  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 73(7) 714 - 728, Jul. 2014, Scientific journal
  

  DOI URL
• Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
  Atsushi Hoshino; Yuichiro Mita; Yoshifumi Okawa; Makoto Ariyoshi; Eri Iwai-Kanai; Tomomi Ueyama; Koji Ikeda; Takehiro Ogata; Satoaki Matoba
  NATURE COMMUNICATIONS, 4 2308 , Aug. 2013, Scientific journal
  

  DOI URL
• p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia
  Atsushi Hoshino; Satoaki Matoba; Eri Iwai-Kanai; Hideo Nakamura; Masaki Kimata; Mikihiko Nakaoka; Maki Katamura; Yoshifumi Okawa; Makoto Ariyoshi; Yuichiro Mita; Koji Ikeda; Tomomi Ueyama; Mitsuhiko Okigaki; Hiroaki Matsubara
  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 52(1) 175 - 184, Jan. 2012, Scientific journal
  

  DOI URL
• p53 Promotes Cardiac Dysfunction in Diabetic Mellitus Caused by Excessive Mitochondrial Respiration-Mediated Reactive Oxygen Species Generation and Lipid Accumulation
  Hideo Nakamura; Satoaki Matoba; Eri Iwai-Kanai; Masaki Kimata; Atsushi Hoshino; Mikihiko Nakaoka; Maki Katamura; Yoshifumi Okawa; Makoto Ariyoshi; Yuichiro Mita; Koji Ikeda; Mitsuhiko Okigaki; Souichi Adachi; Hideo Tanaka; Tetsuro Takamatsu; Hiroaki Matsubara
  CIRCULATION-HEART FAILURE, 5(1) 106 - U254, Jan. 2012, Scientific journal
  

  DOI URL
• TP53 codon 72 polymorphism is associated with pancreatic cancer risk in males, smokers and drinkers
  Takayuki Sonoyama; Akiko Sakai; Yuichiro Mita; Yukiko Yasuda; Hirofumi Kawamoto; Takahito Yagi; Masao Yoshioka; Tetsushige Mimura; Kei Nakachi; Mamoru Ouchida; Kazuhide Yamamoto; Kenji Shimizu
  MOLECULAR MEDICINE REPORTS, 4(3) 489 - 495, May 2011, Scientific journal
  

  DOI URL
• p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress
  Masaki Kimata; Satoaki Matoba; Eri Iwai-Kanai; Hideo Nakamura; Atsushi Hoshino; Mikihiko Nakaoka; Maki Katamura; Yoshifumi Okawa; Yuichiro Mita; Mitsuhiko Okigaki; Koji Ikeda; Tetsuya Tatsumi; Hiroaki Matsubara
  AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 299(6) H1908 - H1916, Dec. 2010, Scientific journal
  

  DOI URL
• Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers
  Yuichiro Mita; Yukiko Yasuda; Akiko Sakai; Hiromasa Yamamoto; Shinichi Toyooka; Mehmet Gunduz; Shunsuke Tanabe; Yoshio Naomoto; Mamoru Ouchida; Kenji Shimizu
  JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 136(2) 249 - 259, Feb. 2010, Scientific journal
  

  DOI URL

MISC

• 過酸化水素によるATPの減少はAMPKの活性化を介してSelenoprotein Pの発現を抑制する。
  三田雄一郎; 細川萩月; 斎藤芳郎; 野口範子
  日本酸化ストレス学会学術集会プログラム・抄録集, 77th, 2024
• パーキンソン病で増加するDJ-1の翻訳後修飾に53番目のシステインが関与する
  松田康平; 三田雄一郎; 浦野泰臣; 西郷和真; 斎藤芳郎; 野口範子
  日本酸化ストレス学会学術集会プログラム・抄録集, 77th, 2024
• グレリンのエネルギー代謝調節における迷走神経求心路の役割
  十枝内 厚次; 岡田 只士; Zaved Waise T.M.; 三田 雄一郎; 迫田 秀之; 中里 雅光
  肥満研究, (一社)日本肥満学会, 25(Suppl.) 256 - 256, Oct. 2019
  

  Permalink
• Serenoprotein P中和抗体を用いた糖尿病治療の開発
  三田 雄一郎; 中山 華穂; 稲荷 尚吾; 野口 範子; 斎藤 芳郎
  日本内分泌学会雑誌, (一社)日本内分泌学会, 94(1) 360 - 360, Apr. 2018
  

  Permalink
• インスリン抵抗性の病態から治療への展開 ヘパトカインセレノプロテインPを標的とするインスリン抵抗性治療薬の開発を目指して
  御簾 博文; 三田 雄一郎; 斎藤 芳郎; 篁 俊成
  糖尿病, (一社)日本糖尿病学会, 61(Suppl.1) S - 29, Apr. 2018
• インスリン抵抗性の病態から治療への展開 ヘパトカインセレノプロテインPを標的とするインスリン抵抗性治療薬の開発を目指して
  御簾 博文; 三田 雄一郎; 斎藤 芳郎; 篁 俊成
  糖尿病, (一社)日本糖尿病学会, 61(Suppl.1) S - 29, Apr. 2018
• 膵β細胞モデルMIN6はセレノプロテインP発現を介して抗酸化システムを維持する
  中尾 昌平; 三田 雄一郎; 斎藤 芳郎; 野口 範子
  生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, 2017年度 [2P - 0374], Dec. 2017
• 膵β細胞モデルMIN6における過剰Selenoprotein Pによるセレン運搬作用を介したERストレス誘導メカニズムの解析
  長村 尭浩; 稲荷 尚吾; 三田 雄一郎; 野口 範子; 斎藤 芳郎
  生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, 2017年度 [2P - 1003], Dec. 2017
• non-coding RNAによるSelenoprotein P翻訳抑制メカニズムの解析
  三田 雄一郎; 斎藤 芳郎; 内田 理沙; 安原 小百合; 横大路 将; 野口 範子
  生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, 2017年度 [3P - 0671], Dec. 2017
• 糖尿病関連タンパク質Selenoprotein Pの翻訳を抑制する内在性long non-coding RNAの発現変化
  内田 理沙; 三田 雄一郎; 横大路 将; 安原 小百合; 斎藤 芳郎; 野口 範子
  生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, 2017年度 [3P - 0672], Dec. 2017
• Decrease of Insulin Secretion is Induced by Excess Selenoprotein P-Improving Effects of Neutralizing Antibody
  Yoshiro Saito; Yuichiro Mita; Kaho Nakayama; Shogo Inari; Takahiro Nagamura; Noriko Noguchi
  FREE RADICAL BIOLOGY AND MEDICINE, 112 156 - 156, Nov. 2017, Summary international conference
  

  DOI URL
• セレノプロテインPの阻害抗体による糖尿病治療効果の解析 インスリン抵抗性および分泌能を改善する抗体医薬の開発
  三田 雄一郎; 中山 華穂; 稲荷 尚吾; 西藤 有希奈; 吉岡 佑弥; 曽谷 奏; 高部 稚子; 御簾 博文; 篁 俊成; 高橋 和彦; 野口 範子; 斎藤 芳郎
  糖尿病, (一社)日本糖尿病学会, 59(Suppl.1) S - 444, Apr. 2016
• Selenoprotein Pの中和抗体による耐糖能異常及びインスリン分泌能の改善
  三田雄一郎; 三田雄一郎; 中山華穂; 稲荷尚吾; 吉岡佑弥; 高部稚子; 御簾博文; 篁俊成; 野口範子; 斎藤芳郎
  日本酸化ストレス学会学術集会プログラム・抄録集, 69th, 2016
• セレノプロテインPの阻害抗体による糖尿病治療効果の解析-インスリン抵抗性および分泌能を改善する抗体医薬の開発
  三田雄一郎; 中山華穂; 稲荷尚吾; 西藤有希奈; 吉岡佑弥; 曽谷奏; 高部稚子; 御簾博文; 篁俊成; 高橋和彦; 野口範子; 斎藤芳郎
  糖尿病(Web), 59(Suppl), 2016
• 膵臓β細胞モデルMIN6は過剰なSelenoprotein Pにより障害を受ける
  稲荷 尚吾; 高部 稚子; 三田 雄一郎; 御簾 博文; 篁 俊成; 野口 範子; 斎藤 芳郎
  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, (公社)日本生化学会, 88回・38回 [4T特L - 10(3P1201)], Dec. 2015
• 1-I-11 血漿セレン含有タンパク質セレノプロテインPを標的とした2型糖尿病の抗体医薬の開発(一般演題要旨,ビタミン・バイオファクター研究のさらなる魅力～大和まほろぱからの発信～,第67回大会講演要旨)
  斎藤 芳郎; 中山 華穂; 三田 雄一郎; 野口 範子
  ビタミン, 公益社団法人 日本ビタミン学会, 89(4) 214 - 214, 2015
• セレンタンパク質研究の最前線 血漿セレノプロテインPによるセレン代謝制御と2型糖尿病
  斎藤 芳郎; 吉岡 佑弥; 三田 雄一郎; 御簾 博文; 田中 睦; 篁 俊成; 野口 範子
  Biomedical Research on Trace Elements, 日本微量元素学会, 25(2) 50 - 50, Jun. 2014
• Tigar (tp53-induced Glycolysis And Apoptosis Regulator) Decreases Glycogenic Energy Metabolism and Deteriorates Left Ventricular Function in Pressure Overload-induced Heart Failure Model
  Yoshifumi Okawa; Eri Iwai-Kanai; Yuichiro Mita; Atsushi Hoshino; Maki Katamura; Makoto Ariyoshi; Satoshi Kaimoto; Kuniyoshi Fukai; Motoki Uchihashi; Satoaki Matoba
  CIRCULATION, 128(22), Nov. 2013, Summary international conference
• Inhibition of Protease Oxidation Preserves Protein Turnover of Mitochondrial Electron Transport Complex and Improves Respiration Capacity in Pressure Overload Heart
  Atsushi Hoshino; Satoaki Matoba; Yuichiro Mita; Eri Iwai-Kanai; Hiroaki Matsubara
  CIRCULATION, 126(21), Nov. 2012, Summary international conference
• Inhibition of Cytosolic p53 Preserves Mitochondrial Integrity and Prevents Cardiac Aging
  Atsushi Hoshino; Satoaki Matoba; Maki Katamura; Yoshifumi Okawa; Makoto Ariyoshi; Satoshi Kaimoto; Yuichiro Mita; Hiroaki Matsubara
  CIRCULATION, 126(21), Nov. 2012, Summary international conference
• Curcumin Prevents Doxorubicin-Induced Cardiotoxicity Through Phosphorylated Bcl-2-Regulated Autophagy
  Maki Katamura; Satoaki Matoba; Eri Iwi-Kanai; Atsushi Hoshino; Yoshifumi Okawa; Yuichiro Mita; Makoto Ariyoshi; Satoshi Kaimoto; Hiroaki Matsubara
  CIRCULATION, 126(21), Nov. 2012, Summary international conference
• p53-Tigar Axis Attenuates Mitophagy Tt Exacerbate Cardiac Damage After Ischemia
  Atsushi Hoshino; Satoaki Matoba; Eri Iwai-Kanai; Maki Katamura; Yoshifumi Okawa; Makoto Ariyoshi; Yuichiro Mita; Hiroaki Matsubara
  CIRCULATION, 124(21), Nov. 2011, Summary international conference
• p53 Promotes Cardiac Dysfunction in Diabetes Mellitus by Excessive Mitochondrial Respiration and Fat/cd36 Upregulation
  Hideo Nakamura; Satoaki Matoba; Eri Iwai-Kanai; Masaki Kimata; Atsushi Hoshino; Mikihiko Nakaoka; Maki Katamura; Yoshihumi Okawa; Yuichiro Mita; Makoto Ariyoshi; Koji Ikeda; Mitsuhiko Okigaki; Hiroaki Matsubara
  CIRCULATION, 124(21), Nov. 2011, Summary international conference
• p53 Promotes Cardiac Aging Through The Inhibition Of Parkin Mediated Mitochondrial Quality Control
  Atsushi Hoshino; Satoaki Matoba; Eri Iwai-Kanai; Maki Katamura; Yoshifumi Okawa; Makoto Ariyoshi; Yuichiro Mita; Hiroaki Matsubara
  CIRCULATION, 124(21), Nov. 2011, Summary international conference
• p53-mediated Acceleration of Mitochondrial Oxygen Consumption Promotes Lipotoxicity via SCO2 in Diabetic Mice
  Hideo Nakamura; Satoaki Matoba; Eri Iwai-Kanai; Masaki Kimata; Atsushi Hoshino; Mikihiko Nakaoka; Maki Katamura; Yoshifumi Okawa; Yuichiro Mita; Tetsuya Tatsumi; Hiroaki Matsubara
  CIRCULATION, 122(21), Nov. 2010, Summary international conference

Research Projects

• The regulation mechanism of oxidation and hypersulfidation in increase of effects of exercise for diabetes prevention
  野口範子; 浦野泰臣; 三田雄一郎; 斎藤芳郎
  JST, KAKENHI, 2024/04 -2027/03, B, Doshisha University
• 超硫黄制御によるインスリン抵抗性改善法の確立
  武田科学振興財団, 医学系研究助成, 2024 -2026, Principal investigator
• Analysis of SECIS regulatory mechanism by noncoding RNA
  三田 雄一郎
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2022/04 -2025/03, Grant-in-Aid for Scientific Research (C), Doshisha University
• Analysis of Insulin Signaling Regulation Mechanisms by persulfide
  yuichiro Mita
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A), 2022/06 -2024/03, Principal investigator, Grant-in-Aid for Transformative Research Areas (A), Doshisha University
• Regulatory mechanism of selenoprotein P expression and its deterioration mechanism of glucose metabolism
  斎藤 芳郎; 外山 喬士; 三田 雄一郎; 星 尚志; 堤 良平
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), 2020/04 -2024/03, Coinvestigator, Grant-in-Aid for Scientific Research (A), Tohoku University
• セレン含有タンパク質Selenoprotein Pを減少させることによって２型糖尿病を改善する食品由来成分の探索
  三田雄一郎
  公益財団法人 食生活研究会, ２０２２年度 研究助成, 2022/04 -2023/03, Principal investigator, 同志社大学
• Establishment of a new cancer therapy targeting the translational regulation of Se containing proteins
  みたゆういちろう
  公益財団法人がん研究振興財団, 令和３年度癌研究助成金 課題A, 2022/04 -2023/03, Principal investigator, 同志社大学
• Analysis of the effect of a novel modification of Parkinson's disease-related protein DJ-1 on the onset and progression of Parkinson's disease
  Takeda Science foundation, 医学系研究助成, 2020 -2023, Principal investigator
• 新規noncoding RNA-L-IST-によるSeP翻訳制御メカニズムの解析
  三田 雄一郎
  日本学術振興会, 科研費 基盤（Ｃ）, 2019/04 -2022/03, Principal investigator, Competitive research funding
• antisense RNAによるSelenoprotein P翻訳抑制機構の解明及び糖尿病治療
  三田 雄一郎
  鈴木謙三記念医科学応用研究財団, 調査研究助成金, 2020/04 -2021/03, Principal investigator, Competitive research funding
• 肝臓由来ペプチドLEAP2による糖尿病治療の開発
  三田 雄一郎
  MSD生命科学財団, 生活習慣病研究助成, 2018/10 -2020/09, Principal investigator, Competitive research funding
• Se含有タンパク質セレノプロテインPを標的とした糖尿病治療法の開発
  三田 雄一郎
  日本応用酵素協会, Front Runner of Future Diabetes Research に関する研究助成, 2018/10 -2019/09, Principal investigator, Competitive research funding
• 内在性antisense RNAによるSe含有タンパク質Selenoprotein P翻訳制御機構の解析
  三田 雄一郎
  日本学術振興会, 科研費 若手（B), 2016/04 -2019/03, Principal investigator, Competitive research funding
• 血漿セレノプロテインPを標的とした新規テーラーメイド２型糖尿病・血管合併症治療薬の研究開発－糖尿病モデル動物による検証及び低分子化
  斎藤芳郎
  科学技術振興機構, 研究成果最適展開支援プログラム（A-STEP）, 2015/04 -2016/03, Competitive research funding
• ＴＩＧＡＲを介する心筋エネルギー代謝フレキシビリティーとＡｐｏｐｔｏｓｉｓ制御
  三田 雄一郎
  日本学術振興会, 科研費 若手（B), 2012/04 -2015/03, Principal investigator, Competitive research funding