Researcher Profile and Settings

researchmap

https://researchmap.jp/a_nakamura

Research funding number

50706629

Research Interests

• 有機合成化学
• 合成化学
• 複素環合成

Research Areas

• Nanotechnology/Materials / Synthetic organic chemistry / 触媒反応
• Life sciences / Pharmaceuticals - chemistry and drug development / 有機合成化学

Research Experience

• Doshisha University, Faculty of Life and Medical Sciences Department of Biomedical Information, 准教授（有期）, 2024/04 - Today
• Kindai University, Faculty of Pharmacy, 講師, 2019/04 - 2024/03
• Kindai University, Faculty of Pharmacy, 助教, 2014/04 - 2019/03

Association Memberships

• THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
• THE PHARMACEUTICAL SOCIETY OF JAPAN
• 日本化学会
• ヨウ素学会
• Japanese society for process chemistry

Published Papers

• Elemental Sulfur-Mediated Aromatic Halogenation
  Junpei Matsuoka; Yuna Yano; Yuuka Hirose; Koushi Mashiba; Nanako Sawada; Akira Nakamura; Tomohiro Maegawa
  The Journal of Organic Chemistry, American Chemical Society (ACS), 89(1) 770 - 777, 19 Dec. 2023, Scientific journal
  

  URLDOI URL
• n-Bu4NI/H2O2-catalyzed mild conversion of hydroxamic acids to carboxylic acids
  Akira Nakamura; Jyunya Morimoto; Maho Taniguchi; Haruka Aoyama; Jiadong He; Tomohiro Maegawa
  Tetrahedron Letters, Elsevier BV, 126 154656 - 154656, Aug. 2023, Scientific journal
  

  DOI URL
• Regioselective Synthesis of 3,4-Disubstituted Isoxazoles by Using a Chalcone-Rearrangement Strategy
  Akira Nakamura; Tohko Kine; Haruna Uenishi; Yuri Maki; Yasuhito Kase; Mayo Takagi; Tomohiro Maegawa
  Synlett, Georg Thieme Verlag KG, 34(11) 1253 - 1258, 06 Feb. 2023, Scientific journal
  

  URLDOI URL
• Development of Synthetic Methods for Heterocyclic Compounds Using the Oxidative Rearrangement of Chalcones and Application to Total Synthesis
  Akira Nakamura
  YAKUGAKU ZASSHI, Pharmaceutical Society of Japan, 143(2) 105 - 110, 01 Feb. 2023, Scientific journal
  

  URLDOI URL
• A concise synthesis of thioaurones via NBS-induced cyclization of MOM-protected 2′-mercaptochalcones
  Akira Nakamura; Fei Rao; Kazuchika Ukiya; Riko Matsunaga; Shin-ichiro Ohira; Tomohiro Maegawa
  Organic & Biomolecular Chemistry, Royal Society of Chemistry (RSC), 21(6) 1134 - 1137, Dec. 2022, Scientific journal
  

  URLDOI URL
• Selective synthesis of 3-formylbenzofuran and 3-acylbenzofuran using a chalcone rearrangement strategy
  Akira Nakamura; Akira Imamiya; Yuichiro Ikegami; Fei Rao; Harumi Yuguchi; Yasuyoshi Miki; Tomohiro Maegawa
  RSC Advances, Royal Society of Chemistry (RSC), 12(47) 30426 - 30431, Oct. 2022, Scientific journal
  

  URLDOI URL
• The Reaction of Ketoximes with Hypervalent Iodine Reagents: Beckmann Rearrangement and Hydrolysis to Ketones
  Tomohiro Maegawa; Yasuyoshi Miki; Ryohei Oishi; Ayumi Maekawa; Kazutoshi Segi; Hiromi Hamamoto; Akira Nakamura
  Synthesis, Georg Thieme Verlag KG, 54(18) 4095 - 4103, Sep. 2022, Scientific journal
  

  URLDOI URL
• One-Pot Synthetic Approaches for the Construction of Isochroman-4-ones and Benzoxazin-3-ones Using O,P-Acetals
  Tomohiro Maegawa; Akira Nakamura; Kouhei Yamamoto; Ryo Murakami; Norihito Kawashita; Kouichi Matsumoto
  Synthesis, Georg Thieme Verlag KG, 53(20) 3862 - 3868, 04 Jun. 2021, Scientific journal
  

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• Deprotection of the Carbazole PMB Group Using Hypervalent Iodine Reagent Combined with N-Hydroxyphthalimide
  Tomohiro Maegawa; Kana Yoshikawa; Takanori Tabata; Kazuma Fujimura; Natsumi Kuraoka; Akira Nakamura; Yasuyoshi Miki
  HETEROCYCLES, The Japan Institute of Heterocyclic Chemistry, 103(2) 1031 - 1031, 2021, Scientific journal
  

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• 超原子価ヨウ素試薬を利用した アルドキシムの官能基選択的酸化反応の開発
  中村光; 加納穂嵩; 田中淳規; 三木康義; 前川智弘
  SIS Report（ヨウ素学会会報）, (23), Nov. 2020, Research institution
• An Improved and Practical Method for Synthesizing of α-Sanshools and Spilanthol
  Akira Nakamura; Kazuki Mimaki; Ken-ichi Tanigami; Tomohiro Maegawa
  Frontiers in Chemistry, Frontiers Media SA, 8, 17 Mar. 2020, Scientific journal
  

  URLDOI URL
• Aromatic Halogenation Using N‑Halosuccinimide and PhSSiMe3 or PhSSPh
  Yuuka Hirose; Mirai Yamazaki; Misa Nogata; Akira Nakamura; Tomohiro Maegawa
  J. Org. Chem., 84 7405 - 7410, Apr. 2019, Scientific journal
• Dehydroxymethyl bromination of alkoxybenzyl alcohols using a hypervalent iodine reagent and lithium bromide
  Ayako Shibata; Sara Kitamoto; Kazuma Fujimura; Yuuka Hirose; Hiromi Hamamoto; Akira Nakamura; Yasuyoshi Miki; Tomohiro Maegawa
  Synlett, 29 2275 - 2278, Sep. 2018, Scientific journal
  

  DOI URL
• Hypervalent Iodine-Mediated Beckmann Rearrangement of Ketoximes
  Ryohei Oishi; Kazutoshi Segi; Hiromi Hamamoto; Akira Nakamura; Tomohiro Maegawa; Yasuyoshi Miki
  Synlett, Georg Thieme Verlag, 29(11) 1465 - 1468, 02 Jul. 2018, Scientific journal
  

  DOI URL
• Direct Synthesis of Chalcones from Anilides with Phenyl Vinyl Ketones by Oxidative Coupling Through C-H Bond Activation
  Tomohiro Maegawa; Ryota Mizui; Miki Urasaki; Kazuma Fujimura; Akira Nakamura; Yasuyoshi Miki
  ACS Omega, American Chemical Society, 3(5) 5375 - 5381, 18 May 2018, Scientific journal
  

  DOI URL
• Construction of Azaisoflavone Derivatives by Hypervalent Iodine Reagent-Mediated Oxidative Rearrangement of 2’-Nitrochalcone
  Akira Nakamura; Junki Tanaka; Junya Morimoto; Tomohiro Maegawa
  Heterocycles, 97, May 2018, Scientific journal
• A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents
  Akira Nakamura; Hodaka Kanou; Junki Tanaka; Akira Imamiya; Tomohiro Maegawa; Yasuyoshi Miki
  Organic and Biomolecular Chemistry, Royal Society of Chemistry, 16(4) 541 - 544, 2018, Scientific journal
  

  URLDOI URL
• Synthesis of 3-acylindoles by oxidative rearrangement of 2-aminochalcones using a hypervalent iodine reagent and cyclization sequence
  Akira Nakamura; Satoshi Tanaka; Akira Imamiya; Reo Takane; Chiaki Ohta; Kazuma Fujimura; Tomohiro Maegawa; Yasuyoshi Miki
  ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOC CHEMISTRY, 15(32) 6702 - 6705, Aug. 2017, Scientific journal
  

  DOI URL
• Transformation of Methylene Acetals to Bromoformates with a Combination of Trimethyl(phenylthio)silane and N-Bromosuccinimide
  Tomohiro Maegawa; Misa Nogata; Yuuka Hirose; Shun Ohgami; Akira Nakamura; Yasuyoshi Miki; Hiromichi Fujioka
  Journal of Organic Chemistry, American Chemical Society, 82(14) 7608 - 7613, 21 Jul. 2017, Scientific journal
  

  URLDOI URL
• HALOGENATION OF DIMETHYL INDOLE-2,3-DICARBOXYLATES USING PhI(OAc)(2) AND ALKALI METAL HALIDE
  Yasuyoshi Miki; Yukari Hirata; Noriko Makino; Yuuka Hirose; Misa Nogata; Akira Nakamura; Hiromi Hamamoto; Tomohiro Maegawa
  HETEROCYCLES, PERGAMON-ELSEVIER SCIENCE LTD, 94(7) 1269 - 1279, Jul. 2017, Scientific journal
  

  DOI URL
• 2-ARYLQUINOLINE SYNTHESIS FROM Cbz-PROTECTED 2-AMINO-CHALCONE MEDIATED BY BF3 center dot Et2O
  Tomohiro Maegawa; Misa Nogata; Takaya Honda; Akira Nakamura; Yasuyoshi Miki
  HETEROCYCLES, PERGAMON-ELSEVIER SCIENCE LTD, 95(1) 608 - 614, Jan. 2017, Scientific journal
  

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• Metal-Free Oxidative Cross-Coupling Reaction of Thiophene Iodonium Salts with Pyrroles
  Koji Morimoto; Akira Nakamura; Toshifumi Dohi; Yasuyuki Kita
  EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, WILEY-V C H VERLAG GMBH, 25(25) 4294 - 4297, Sep. 2016, Scientific journal
  

  DOI URL
• Stabilized pyrrolyl iodonium salts and metal-free oxidative cross-coupling
  Koji Morimoto; Yusuke Ohnishi; Daichi Koseki; Akira Nakamura; Toshifumi Dohi; Yasuyuki Kita
  ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOC CHEMISTRY, 14(38) 8947 - 8951, 2016, Scientific journal
  

  DOI URL
• DECARBOXYLATIVE HALOGENATION OF INDOLECARBOXYLIC ACIDS USING HYPERVALENT IODINE(III) REAGENT AND ITS APPLICATION TO THE SYNTHESIS OF POLYBROMOINDOLES
  Hiromi Hamamoto; Hideaki Umemoto; Misako Umemoto; Chiaki Ohta; Emi Fujita; Akira Nakamura; Tomohiro Maegawa; Yasuyoshi Miki
  HETEROCYCLES, PERGAMON-ELSEVIER SCIENCE LTD, 91(3) 561 - 572, Mar. 2015, Scientific journal
  

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• Reactions of 2-[Lithio(trimethylsilyl)methyl]-2H-tetrazoles: Synthesis of 2-[1-(Trimethylsilyl) alkyl]-2H-tetrazoles and (2H-Tetrazol-2-yl) acetates
  Hideaki Umemoto; Takuya Onaka; Yasuyoshi Miki; Akira Nakamura; Tomohiro Maegawa
  SYNLETT, GEORG THIEME VERLAG KG, 26(2) 205 - 208, Jan. 2015, Scientific journal
  

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• Enantioselective, Desymmetrizing, Bromolactonization Reactions of Symmetric Olefinic Dicarboxylic Acids
  Kenichi Murai; Junki Nakajima; Akira Nakamura; Norimichi Hyogo; Hiromichi Fujioka
  CHEMISTRY-AN ASIAN JOURNAL, WILEY-V C H VERLAG GMBH, 9(12) 3511 - 3517, Dec. 2014, Scientific journal
  

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• THE REACTION OF 2-((TRIMETHYLSILYL)METHYL)-2H-TETRAZOLES WITH ALDEHYDES AND KETONES IN THE PRESENCE OF 1,8-DIAZABICYCLO [5.4.0]UNDEC-7-ENE
  Hideaki Umemoto; Takuya Onaka; Yasuyoshi Miki; Akira Nakamura; Tomohiro Maegawa
  HETEROCYCLES, PERGAMON-ELSEVIER SCIENCE LTD, 89(11) 2545 - 2553, Nov. 2014, Scientific journal
  

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• [Cu(OH)(TMEDA)](2)Cl-2-Catalyzed Regioselective 2-Arylation of 5-Substituted Tetrazoles with Boronic Acids under Mild Conditions
  Takuya Onaka; Hideaki Umemoto; Yasuyoshi Miki; Akira Nakamura; Tomohiro Maegawa
  JOURNAL OF ORGANIC CHEMISTRY, AMER CHEMICAL SOC, 79(14) 6703 - 6707, Jul. 2014, Scientific journal
  

  DOI URL
• N1-Selective Oxidative C similar to N Coupling of Azoles with Pyrroles Using a Hypervalent Iodine Reagent
  Koji Morimoto; Yusuke Ohnishi; Akira Nakamura; Kazuma Sakamoto; Toshifumi Dohi; Yasuyuki Kita
  ASIAN JOURNAL OF ORGANIC CHEMISTRY, WILEY-V C H VERLAG GMBH, 3(4) 382 - 386, Apr. 2014, Scientific journal
  

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• Kinetic Resolution of beta-Substituted Olefinic Carboxylic Acids by Asymmetric Bromolactonization
  Kenichi Murai; Tomoyo Matsushita; Akira Nakamura; Norimichi Hyogo; Junki Nakajima; Hiromichi Fujioka
  ORGANIC LETTERS, AMER CHEMICAL SOC, 15(10) 2526 - 2529, May 2013, Scientific journal
  

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• C3-Symmetric Trisimidazoline-Catalyzed Enantioselective Bromolactonization of Internal Alkenoic Acids
  Kenichi Murai; Akira Nakamura; Tomoyo Matsushita; Masato Shimura; Hiromichi Fujioka
  CHEMISTRY-A EUROPEAN JOURNAL, WILEY-V C H VERLAG GMBH, 18(27) 8448 - 8453, Jul. 2012, Scientific journal
  

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• C-3-Symmetric chiral trisimidazoline: the role of a third imidazoline and its application to the nitro Michael reaction and the alpha-amination of beta-ketoesters
  Kenichi Murai; Shunsuke Fukushima; Akira Nakamura; Masato Shimura; Hiromichi Fujioka
  TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, 67(26) 4862 - 4868, Jul. 2011, Scientific journal
  

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• Asymmetric Bromolactonization Catalyzed by a C3-Symmetric Chiral Trisimidazoline
  Kenichi Murai; Tomoyo Matsushita; Akira Nakamura; Shunsuke Fukushima; Masato Shimura; Hiromichi Fujioka
  Angewandte Chemie, 122(48) 9360 - 9363, Oct. 2010, Scientific journal
  

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• Asymmetric Bromolactonization Catalyzed by a C-3-Symmetric Chiral Trisimidazoline
  Kenichi Murai; Tomoyo Matsushita; Akira Nakamura; Shunsuke Fukushima; Masato Shimura; Hiromichi Fujioka
  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, WILEY-V C H VERLAG GMBH, 49(48) 9174 - 9177, 2010, Scientific journal
  

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Research Projects

• N―ヒドロキシアミンの特性に基づく官能基選択的反応の開発
  中村 光
  文部科学省: 科学研究費補助金(若手研究(B)), 2019/04 -2022/03, Principal investigator, Competitive research funding
• 環境調和を指向したヒドロキサム酸の新規変換反応の開発研究
  近畿大学, 奨励研究助成金, 2020/04 -2021/03, Principal investigator
• アゾール類の多様な誘導体合成法の開発と機能性化合物合成への応用
  中村 光
  文部科学省, 科学研究費補助金(若手研究(B)), 2015/04 -2018/03, Principal investigator, Competitive research funding
• C3対称キラル活性化剤を利用した新規触媒反応の開発研究
  立命館大学, 研究推進プログラム（若手研究）, 2013/04 -2014/03, Principal investigator

Teaching Experience

• 卒業研究
  近畿大学
• 基礎ゼミ
  近畿大学
• 総合薬学研究2
  近畿大学
• 総合薬学研究1
  近畿大学
• 創薬科学演習
  近畿大学
• 創薬科学実習2
  近畿大学
• 有機化学生薬学実習
  近畿大学
• 基礎薬科学実習
  近畿大学
• 基礎化学英語
  近畿大学
• 化学英語
  近畿大学
• 有機反応化学
  近畿大学
• 合成化学
  近畿大学
• 新創薬科学研究コース１
  近畿大学
• 新創薬科学研究コース2
  近畿大学
• オープンラボ２
  近畿大学
• オープンラボ１
  近畿大学
• 薬学英語
  近畿大学
• 総合薬学研究３
  近畿大学
• グローバル創薬演習
  近畿大学
• メディシナルケミストリー
  近畿大学