| HATA Toshimichi |  |
| Faculty of Psychology Department of Psychology | |
| Professor |
Last Updated :2025/05/08
Researcher Profile and Settings
researchmap
Research Areas
Research Experience
- Doshisha University, Faculty of Psychology Department of Psychology, 教授, 2014/04 - Today
- Doshisha University, Faculty of Psychology Department of Psychology, 准教授, 2008/04 - 2014/03
- Doshisha University, Faculty of Letters, 准教授, 2008/04 - 2009/03
- 国立大学法人浜松医科大学医学部教務員, 2005 - 2008
- Tezukayama University, 2000 - 2005
- 日本学術振興会特別研究員（ＤＣ, ＰＤ）, 1998 - 2000
Education
- Doshisha University, 文学研究科, 心理学専攻, - 2002
- Doshisha University, Graduate School, Division of Letters, - 2002
- Doshisha University, 文学研究科, 心理学専攻, - 1996
- Doshisha University, Graduate School, Division of Letters, - 1996
- Doshisha University, Faculty of Letters, 文化学科心理学専攻, - 1994
- Doshisha University, Faculty of Literature, - 1994
Association Memberships
MISC
- Cholinergic interneurons in the dorsal striatum play an important role in the acquisition of duration memory.
Masahiko Nishioka; Toshimichi Hata
The European journal of neuroscience, 59(11) 3061 - 3073, Jun. 2024 - Intra-dorsal striatal acetylcholine M1 but not dopaminergic D1 or glutamatergic NMDA receptor antagonists inhibit consolidation of duration memory in interval timing
Masahiko Nishioka; Taisuke Kamada; Atsushi Nakata; Naoko Shiokawa; Aoi Kinoshita; Toshimichi Hata
Behavioural Brain Research, Elsevier BV, 419 113669 - 113669, Feb. 2022 - Intra-dorsal striatal acetylcholine M1 but not dopaminergic D1 or glutamatergic NMDA receptor antagonists inhibit the consolidation of duration memory in interval timing
Masahiko Nishioka; Taisuke Kamada; Atsushi Nakata; Naoko Shiokawa; Aoi Kinoshita; Toshimichi Hata
bioRxiv, Cold Spring Harbor Laboratory, 419 113669 - 113669, 25 May 2021, Technical report - Effects of Medial Prefrontal D1 Dopamine Receptor Blockade on Accuracy and Precision in a Peak Interval Procedure
Xingzhi LIU; Toshimichi HATA
Japanese Journal of Physiological Psychology and Psychophysiology, Japanese Society for Physiological Psychology and Psychophysiology, 38(1) 21 - 33, 30 Apr. 2020 - A Task for Assessing the Impact of a Partner on the Speed and Accuracy of Motor Performance in Rats.
Yayoi Sekiguchi; Toshimichi Hata
Journal of Visualized Experiments : JoVE, (152), 17 Oct. 2019 - Basolateral amygdala inactivation eliminates fear-induced underestimation of time in a temporal bisection task.
Taisuke Kamada; Toshimichi Hata
Behavioural Brain Research, 356 227 - 235, 01 Jan. 2019 - Effects of the mere presence of conspecifics on the motor performance of rats: Higher speed and lower accuracy
Yayoi Sekiguchi; Toshimichi Hata
Behavioural Processes, 159 18 , 2019 - Insular cortex inactivation generalizes fear-induced underestimation of interval timing in a temporal bisection task
Taisuke Kamada; Toshimichi Hata
Behavioural Brain Research, Elsevier B.V., 347 219 - 226, 16 Jul. 2018 - Post-acquisition hippocampal blockade of the NMDA receptor subunit GluN2A but not GluN2B sustains spatial reference memory retention
Keisuke Shinohara; Toshimichi Hata
Neurobiology of Learning and Memory, Academic Press Inc., 147 1 - 8, 01 Jan. 2018 - The effect of response deadlines on the performance of sequential lever-pressing task in rats (Rattus norvegicus)
Yayoi Sekiguchi; Toshimichi Hata
The Japanese Journal of Animal Psychology, THE JAPANESE SOCIETY FOR ANIMAL PSYCHOLOGY, 66(2) 131 - 140, 2016 - A stimulus previously paired with an electric footshock increases the point of subjective equality in timing in rats (Rattus norvegicus)
Taisuke Kamada; Toshimichi Hata
The Japanese Journal of Animal Psychology, THE JAPANESE SOCIETY FOR ANIMAL PSYCHOLOGY, 66(2) 121 - 130, 2016 - Involvement of hippocampal NMDA receptors in deterioration of spatial memory
篠原恵介; 畑敏道
行動科学, 日本行動科学学会, 53(2) 137 - 146, 2015 - Post-acquisition hippocampal NMDA receptor blockade sustains retention of spatial reference memory in Morris water maze
Keisuke Shinohara; Toshimichi Hata
Behavioural Brain Reserch, ELSEVIER SCIENCE BV, 259 261 - 267, Feb. 2014 - Effect of coffee cue presentation on desire for coffee and cognitive performance
M Fukuda; T Hata; S Komatsu; K Aoyama
The Japanese Journal of Psychonomic Science, 33(1) 28 - 34, 2014 - 獲得後のNMDA受容体阻害は空間記憶保持を向上させる
篠原恵介; 畑 敏道
心理学研究, 84(6) 618 - 624, 2014 - ラットの忘却におけるNMDA受容体の関与 Morris型水迷路課題の訓練後における海馬NMDA受容体の阻害は記憶保持の低下を抑制する
篠原恵介; 畑敏道
日本心理学会大会発表論文集, 77th, 2013 - Intra-ventral tegmental area or intracerebroventricular orexin-A increases the intra-cranial self-stimulation threshold via activation of the corticotropin-releasing factor system in rats
Toshimichi Hata; Jihuan Chen; Kosuke Ebihara; Yukari Date; Yasushi Ishida; Daiichiro Nakahara
European Journal of Neuroscience, WILEY-BLACKWELL, 34(5) 816 - 826, Sep. 2011 - Glutamate - A forgotten target for interval timing
Toshimichi Hata
Frontiers in Integrative Neuroscience, 5(27) 43467 , 2011 - Increase in ICSS threshold with orexin A is blocked by an antagonism of CRF receptor
Toshimichi Hata; Kohsuke Ebihara; Yukari Date; Yasushi Ishida; Daiichiro Nakahara
NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 65 S256 - S256, 2009, Summary international conference - Intracranial self-stimulation enhances neurogenesis in hippocampus of adult mice and rats
T. Takahashi; Y. Zhu; T. Hata; C. Shimizu-Okabe; K. Suzuki; D. Nakahara
Neuroscience, PERGAMON-ELSEVIER SCIENCE LTD, 158(2) 402 - 411, Jan. 2009 - Hippocampal acetylcholine efflux increases during negative patterning and elemental discrimination in rats
Toshimichi Hata; Ken'ichiro Kumai; Hiroshige Okaichi
Neuroscience Letters, ELSEVIER IRELAND LTD, 418(2) 127 - 132, May 2007 - Orexin attenuates the rewarding effect of intracranial self-stimulation in rats
Toshimichi Hata; Jihuan Chen; Taro Takahashi; Shuibo Gao; Yasushi Ishida; Yukari Date; Daiichiro Nakahara
NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 58 S227 - S227, 2007, Summary international conference - Medial prefrontal cortex and precision of temporal discrimination: a lesion, microinjection, and microdialysis study
Hata, T; Okaichi, H
Neuroscience Research, 49(1) 81 - 89, 2004 - IP003 内側中隔コリン作動性ニューロン損傷がラットの時間弁別行動に与える効果
畑 敏道; 青山 謙二郎; 岡市 広成
動物心理学研究, 日本動物心理学会, 53(2) 101 - 101, 25 Dec. 2003 - On a role of cholinergic and dopaminergic system on temporal discrimination in rats
HATA Toshimichi
Japanese Journal of Physiological Psychology and Psychophysiology, Japanese Society for Physiological Psychology and Psychophysiology, 21(1) 49 - 58, 2003 - O-2C-6 ラットの時間弁別行動に与える前頭前野スコポラミン投与の効果(日本動物心理学会第61回大会発表要旨)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 51(2) 100 - 100, 25 Dec. 2001 - スコポラミン慢性投与によるラットの時間弁別行動の感度の低下
畑 敏道; 岡市広成
心理学研究, 71(6) 454 - 461, 2001 - P-05 ラットの時間評価時における前頭前野ACh濃度の変化(日本動物心理学会第60回大会発表要旨)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 50(2) 291 - 291, 25 Dec. 2000 - ラットの時間弁別行動における中枢アセチルコリン（神経）系の役割について
畑 敏道
動物心理学研究, 50(1) 141 - 150, 2000 - 未来を表す日本語表現が持つ時間的距離感の不連続性
畑 敏道; 岡市広成
行動科学, 日本行動科学学会, 39(1) 43479 - 14, 2000 - P-1-05 慢性scopolamine投与によるラットの時間評価能力の悪化(日本動物心理学会第59回大会発表)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 49(1) 72 - 72, 20 Jun. 1999 - ラットの時間弁別行動に与える海馬采-脳弓損傷の効果
畑 敏道; 岡市広成
心理学研究, 69(4) 304 - 309, 1998 - Morris型水迷路におけるラットの場所学習の発達
畑 敏道; 岡市広成
動物心理学研究, 47(1) 43535 , 1997 - O-3-2 ラットの時間弁別行動に与える抗コリン薬の効果(2)(日本動物心理学会第56回大会発表要旨)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 46(2) 96 - 96, 25 Dec. 1996 - PB01 ラットの時間弁別行動に与える坑コリン薬の効果(日本動物心理学会第55回大会発表要旨)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 45(2) 125 - 125, 25 Mar. 1996 - Morris型水迷路におけるラットの空間学習行動の発達的研究(日本動物心理学会第54回大会発表要旨)
畑 敏道; 岡市 広成
動物心理学研究, 日本動物心理学会, 44(1) 46 - 46, 25 Mar. 1995
Books etc
- n/a
Toshimichi Hata
Dec. 2022, Joint work, 第10章 神経・生理心理学 - ようこそ、心理学部へ
同志社大学心理学部
Mar. 2022, Joint work, 第5章 生理心理学 - 神経・生理心理学 基礎と臨床，わたしとあなたをつなぐ「心の脳科学」
Apr. 2020, Contributor - 生理心理学と精神生理学 第II巻
北大路書房, 2017, Contributor, Scholarly book - 心理学からみた食べる行動:基礎から臨床までを科学する
2017, Contributor, Scholarly book - 生理心理学と精神生理学 第I巻 基礎
北大路書房, 2017, Contributor, Scholarly book - 動物たちは何を考えている?−動物心理学の挑戦−
技術評論社, 2015, Contributor, Scholarly book - 現代心理学シリーズ4 動機づけと情動
培風館, 2015, Contributor, Scholarly book - 心理学概論（第２版）
ナカニシヤ出版, 2014, Contributor, Scholarly book - 心理学概論
ナカニシヤ出版, 2006, Contributor, Scholarly book
Presentations
- Intra-dorsal striatal acetylcholine M1 but not glutamatergic NMDA receptor antagonists inhibit the consolidation of duration memory in interval timing
Masahiko Nishioka; Toshimichi Hata
30 Oct. 2021, Oral presentation - 時間と生理心理学
畑 敏道
23 May 2021, Nominated symposium - A mixed injection of NMDA and M1 receptor blockers into the dorsal striatum impaired the acquisition of memory for duration in a peak interval procedure.
2018, Poster presentation - Effects of competition on the motor performance of rats
2018, Poster presentation - The GABAA receptors in the dorsal striatum control interval timing.
2018, Poster presentation - Effects of AP5 or muscimol infusion into the retrosplenial cortex on the retrieval of spatial memory in rats.
2018, Poster presentation - A pharmacological investigation of the function of delta-opioid receptors in temporal discrimination.
2018, Poster presentation - Do rats avoid foods delivery to a free-riding conspecific?
2018, Poster presentation - The striatal GABAA receptor involves in the fear-induced under estimation of time.
Neuro2018, 2018, Poster presentation - 背側海馬内muscimol投与が時程の記憶形成に与える効果
日本生理心理学会第36回大会, 2018, Poster presentation - A mixed injection of NMDA and M1 receptor blockers into the dorsal striatum impaired the acquisition of memory for duration in a peak interval procedure.
日本動物心理学会第78回大会 広島, 2018, Poster presentation - Effects of competition on the motor performance of rats
日本動物心理学会第78回大会, 2018, Poster presentation - The GABAA receptors in the dorsal striatum control interval timing.
日本動物心理学会第78回大会, 2018, Poster presentation - Effects of AP5 or muscimol infusion into the retrosplenial cortex on the retrieval of spatial memory in rats.
日本動物心理学会第78回大会, 2018, Poster presentation - A pharmacological investigation of the function of delta-opioid receptors in temporal discrimination.
日本動物心理学会第78回大会, 2018, Poster presentation - ラットはフリーライダーへの報酬分配を避けるのか?
日本心理学会第85回大会, 2018, Poster presentation - The striatal GABAA receptor involves in the fear-induced under estimation of time.
日本神経科学第41回大会, 2018, Poster presentation - 脳の中に、時計をさがしに
畑 敏道
関西心理学会第129回大会, 2017, Invited oral presentation, 京都 - Inactivation of the insular cortex suppresses underestimation of interval timing induced by the fear-conditioned stimulus in rats.
Neuro2017, 2017, Poster presentation - Time limit decreases the accuracy of the sequential lever-press performance in rats.
1st Timing Research Forum, 2017, Poster presentation - Dorsal Striatum Inactivation Disrupts Temporal Discrimination, but not Tone Frequency Discrimination in a Bisection Task
1st Timing Research Forum, 2017, Poster presentation - Inactivation of the insular cortex suppresses underestimation of interval timing induced by the fear-conditioned stimulus in rats.
日本神経科学学会第40回大会, 2017, Poster presentation - ラットのインターバルタイミングにおける背側線条体の役割
動物心理学会第77回大会, 2017, Poster presentation - ラット(Rattus norvegicus)において他個体の存在が運動課題の遂行の速度および 正確さに及ぼす影響の検討
動物心理学会77回大会, 2017, Poster presentation - The brain mechanisms modulating and producing interval timing: the role of the amygdala and the dorsal striatum.
HATA Toshimichi
18th International Congress of Psychology, 2016, Yokohama - 時間評価における背側線条体の役割〜SBFモデルの妥当性の検討
畑 敏道
第25回海馬と高次脳機能学会, 2016, Invited oral presentation, 京都 - Memory forgetting and NMDA receptor: Post-acquisition chronic micro infusion of NVP-AAM077 into dorsal hippocampus subsequently impairs the performance at reversal learning task in Morris water maze in rats.
Neuro2016, 2016 - NMDA receptors in the retrosplenial cortex contribute to the retrieval of spatial memory in rats.
Neuro2016, 2016, Poster presentation - An injection of NMDA type receptor blocker into the dorsal striatum did not impaire the acquisition of memory for duration in a peak interval procedure.
ICP2016, 2016, Poster presentation - Do female rats behave pro-socially?
ICP2016, 2016, Poster presentation - The effect of deadlines on the performance of theladder rung walking task in rats.
2016, Poster presentation - The role of the insular cortex on underestimation of duration induced by the fear-conditioned to-be-timed stimulus in a temporal bisection task in rats.
2016 - Memory forgetting and NMDA receptor: Post-acquisition chronic micro infusion of NVP-AAM077 into dorsal hippocampus subsequently impairs the performance at reversal learning task in Morris water maze in rats.
第39回神経科学大会, 2016 - NMDA receptors in the retrosplenial cortex contribute to the retrieval of spatial memory in rats.
第39回神経科学大会, 2016, Poster presentation - An injection of NMDA type receptor blocker into the dorsal striatum did not impaire the acquisition of memory for duration in a peak interval procedure.
ICP2016, 2016, Poster presentation - Do female rats behave pro-socially?
ICP2016, 2016, Poster presentation - 部分的な手がかりからの想起における脳梁膨大部後部皮質内NMDA受容体阻害の効果
関西心理学会第128回大会, 2016 - The effect of deadlines on the performance of theladder rung walking task in rats.
第76回日本動物心理学会大会, 2016, Poster presentation - The role of the insular cortex on underestimation of duration induced by the fear-conditioned to-be-timed stimulus in a temporal bisection task in rats.
日本動物心理学会第76回大会, 2016 - Post-acquisition blockade of hippocampal GluN2A-containing NMDA receptors prevents forgetting in the Morris water maze in rats.
The 75th Annual Meeting of the Japanese Society for Animal Psychology, 2015 - The role of the amygdala in fear-induced underestimation of duration in rats.
The 75th Annual Meeting of the Japanese Society for Animal Psychology., 2015 - Sequential lever-pressing performance under response deadline in rats.
The 75th Annual Meeting of the Japanese Society for Animal Psychology., 2015, Poster presentation - Effect of an intra-dorsal striatum injection of NMDA receptors blocker, AP5, on the formation of temporal memory in rats.
The 75th Annual Meeting of the Japanese Society for Animal Psychology., 2015, Poster presentation - Do rats withhold food rewards to a "free rider"?
The 75th Annual Meeting of the Japanese Society for Animal Psychology, 2015, Poster presentation - The effects of post-acquisition blockade of hippocampal NMDA receptor subunit GluN2A and/or GluN2B on spatial memory forgetting.
Society for Neuroscience 44th Annual Meeting, 2015, Poster presentation - An intra-amygdala injection of the GABAA agonist, muscimol, prevents fear-induced underestimation of duration.
Society for Neuroscience 44th Annual Meeting, 2015 - Post-acquisition blockade of hippocampal GluN2A-containing NMDA receptors prevents forgetting in the Morris water maze in rats.
第75回日本動物心理学会, 2015 - The role of the amygdala in fear-induced underestimation of duration in rats.
第75回日本動物心理学会, 2015 - Sequential lever-pressing performance under response deadline in rats.
第75回日本動物心理学会, 2015, Poster presentation - Effect of an intra-dorsal striatum injection of NMDA receptors blocker, AP5, on the formation of temporal memory in rats.
第75回日本動物心理学会, 2015, Poster presentation - Do rats withhold food rewards to a "free rider"?
第75回日本動物心理学会, 2015, Poster presentation - 蔗糖の摂取がラットの空間記憶の固定化に与える影響
第79回日本心理学会大会, 2015, Poster presentation - 間隔二等分課題における個別試行分析の試み
第79回日本心理学会大会, 2015, Poster presentation - The effects of post-acquisition blockade of hippocampal NMDA receptor subunit GluN2A and/or GluN2B on spatial memory forgetting.
Society for Neuroscience 44th Annual Meeting, 2015, Poster presentation - An intra-amygdala injection of the GABAA agonist, muscimol, prevents fear-induced underestimation of duration.
Society for Neuroscience 44th Annual Meeting, 2015 - Post-acquisition hippocampal GluN2B-containing NMDA recptors blockade prevents "forgetting" in the Morris water maze in rats.
The 74th Annual Meeting of the Japanese Society for Animal Psychology., 2014 - A competitive task attenuates the dysfunction of skilled movement in the animal model of Parkinson's disease.
The 74th Annual Meeting of the Japanese Society for Animal Psychology., 2014, Poster presentation - The effects of post-acquisition blockade of GluN2B-containing NMDA receptors on "forgetting" and subsequent reversal learning in the Morris water maze.
Society for Neuroscience 44th annual meeting, 2014, Poster presentation - Effect of an intra-dorsal striatum injection of a muscarinic acetylcholine m1 receptors blocker, pirenzepin, on memorization of duration in rats.
Society for Neuroscience 44th annual meeting., 2014, Poster presentation - PGC-1α expression is not essential for endurance training–induced increase in myoglobin expression in skeletal muscle.
American College of Sports Medicine 61st Annual Meeting, 2014, Poster presentation - Post-acquisition hippocampal GluN2B-containing NMDA recptors blockade prevents "forgetting" in the Morris water maze in rats.
第74回日本動物心理学会, 2014 - Is interval ltiming modified by conditioned fear in rats?: An investivation using a self-start short/long discrimination task.
第74回日本動物心理学会, 2014, Poster presentation - A competitive task attenuates the dysfunction of skilled movement in the animal model of Parkinson's disease.
第74回日本動物心理学会, 2014, Poster presentation - The activity of c-Fos and EGR-1 in the dorsal striatum increases during memorization of duration.
第74回日本動物心理学会, 2014, Poster presentation - The effects of post-acquisition blockade of GluN2B-containing NMDA receptors on "forgetting" and subsequent reversal learning in the Morris water maze.
Society for Neuroscience 44th annual meeting, 2014, Poster presentation - Effect of an intra-dorsal striatum injection of a muscarinic acetylcholine m1 receptors blocker, pirenzepin, on memorization of duration in rats.
Society for Neuroscience 44th annual meeting., 2014, Poster presentation - Post-training hippocampal NMDA receptor blockade suppresses “forgetting” in the Morris water maze spatial memory task.
Society for Neuroscience 43th annual meeting., 2013, Poster presentation - The effect of conditioned fear on interval timing in rats.
Society for Neuroscience 43th annual meeting,, 2013, Poster presentation - 注意を向ける方向と触覚の有無がゴムの手の錯覚 に与える効果
注意を向ける方向と触覚の有無がゴムの手の錯覚 に与える効果, 2013, Poster presentation - 行動課題によるコーヒーcravingの測定
日本心理学会第77回大会, 2013, Poster presentation - ラットの忘却におけるNMDA受容体の関与
日本心理学会第77回大会, 2013, Poster presentation - 条件性恐怖はラットにおいて時間の過小評価と時間弁別精度の低下を引き起こす
日本動物心理学会第73回大会, 2013 - Post-training hippocampal NMDA receptor blockade suppresses “forgetting” in the Morris water maze spatial memory task.
Society for Neuroscience 43th annual meeting., 2013, Poster presentation - The effect of conditioned fear on interval timing in rats.
Society for Neuroscience 43th annual meeting,, 2013, Poster presentation - Hippocampal acetylcholine efflux is enhanced during negative patterning discrimination task compared with elemental discrimination task in rats
HATA Toshimichi
ICSP 16th Biennial meeting, 2012, Invited oral presentation, Jaén, Spain - 心は脳にある。時間評価の行動科学と行動神経科学
畑 敏道
日本心理学会公開シンポジウム 基礎心理学の展開シリーズ 心理学における動物実験の実際, 2012, Invited oral presentation, 兵庫医療大学 - Post-training N-methyl-D-aspartate receptor blockade facilitates spatial memory retention in rats performing the Morris water maze task.
Society for Neuroscience 42th annual meeting, 2012, Poster presentation - Effect of NMDA receptor blockade on acquisition of memory for duration in rats.
Society for Neuroscience 42th annual meeting, 2012, Poster presentation - 水迷路課題獲得後の AP5 脳室内慢性投与はラットの空間記憶の忘却を抑制する
日本動物心理学会第72回大会, 2012 - 施灸による前頭前野と線条体におけるドーパミン分泌
日本生理学会第88回大会・第116回日本解剖学会総会・全国学術集会, 2011, Poster presentation - 背内側線条体内ＮＭＤＡ受容体拮抗薬ＡＰ‐５の投与がラットの時程の学習に及ぼす影響
日本動物心理学会第71回大会, 2011, Poster presentation - ラットにおける自発的走行が空間記憶の獲得に与える効果
日本動物心理学会第71回大会, 2011, Poster presentation - 保持期間中のNMDA受容体阻害剤AP5脳室内慢性投与が忘却に与える影響の検討
日本動物心理学会第71回大会, 2011, Poster presentation - ラットの時程の記憶の獲得に与えるNMDA型グルタミン酸受容体阻害薬MK-801投与の効果
日本動物心理学会第71回大会, 2011, Poster presentation - Enhanced locomotor sensitization to cocaine in b2-microglobulin deficient mice.
7th FENS forum, 2010, Poster presentation - 条件性場所選好課題を用いたラベンダーオイルの報酬特性の検討
日本動物心理学会第70回大会, 2010 - MK-801の脳室内投与が時間弁別行動に及ぼす効果
日本動物心理学会第70回大会, 2010, Poster presentation - ラットにおける自発的走行が空間記憶課題に及ぼす効果についての検討
日本動物心理学会第70回大会, 2010, Poster presentation - 脳内報酬系における視床下部ペプチド・オレキシンの役割
畑 敏道
日本行動科学学会第25回ウィンターカンファレンス, 2009, Invited oral presentation, 妙高高原 - Increase in ICSS threshold with orexin A is blocked by an antagonism of CRF receptor.
Neuro2009, 2009, Poster presentation - ラットにおけるラベンダー精油の報酬特性の検討 ̶ 条件性場所選好課題を用いて
日本動物心理学会第69回大会, 2009, Poster presentation - Intracranial self-stimulation enhances neurogenesin in the rodent brain
Neuro2007, 2007, Poster presentation - A novel model of chronic cocaine self-administration in the mouse
Keystone Symposium: Neurobiology of Addiction, 2007 - β2-mおよびperforin KOマウスにおける自発的活動量とコカイン誘発性活動量の増加
第34回日本脳科学会, 2007 - Orexin attenuates the rewarding effect of intracranial self-stimulation in rats
第30回日本神経科学大会, 2007 - Circadian rhythm of cocaine self-administration behavior in mice
From Molecular Clocks to Human Health Symposium, 2007 - Intra-VTA orexin-A increases intracranial self-stimulation threshold and dopamine efflux in the stress-related brain regioins in rats
Society for Neuroscience 37th annual meeting, 2007, Poster presentation - Stable, escalation and binge models of cocaine self-administration in mice
Society for Neuroscience 37th annual meeting, 2007, Poster presentation - 腹側被蓋野へのオレキシンA投与は脳内自己刺激報酬閾値と扁桃体中心核、分界条床核でのドーパミン放出量を増加させる
第18回マイクロダイアリシス研究会, 2007 - 腹側被蓋野へのオレキシン投与が 前頭前野、側坐核coreおよびshell領野でのドーパミン放出に与える効果
第17回マイクロダイアリシス研究会, 2006 - 海馬依存性学習とアセチルコリン: マイクロダイアリシスによる検討
第16回マイクロダイアリシス研究会, 2005 - 時間評価の生理心理学的研究の応用可能性
畑 敏道
日本動物心理学会第64回大会サテライトシンポジウム, 2004, Invited oral presentation, 大阪市立大学 - The Efffect of MK-801 on forgetting of spatial memory: Is forgetting supported by positive processes?
International Symposium on Comparative Study of Hippocampal Functions, 2004 - Repeated MK-801 injection after acquisition of spatial task prevents rats from forgetting spatial location
8th European Congress of Psychology, 2003, Poster presentation - 内側中隔コリン作動性ニューロン損傷がラットの時間弁別行動に与える効果
日本動物心理学会第63回大会, 2003, Poster presentation - ラットの時間弁別行動に与える前頭前野スコポラミン投与の効果
日本動物心理学会第61回大会, 2001 - ラットの時間弁別行動に与える前頭前野損傷の効果
日本心理学会第65回大会, 2001, Poster presentation - ラットの時間評価時における前頭前野ACh濃度の変化
日本動物心理学会第60回大会, 2000, Poster presentation - Scopolamine impairs the ability of time estimation
17th International Congress of Psychology, 2000, Poster presentation - 慢性scopolamine投与によるラットの時間評価能力の悪化
日本動物心理学会第59回大会, 1999, Poster presentation - ラットの時間弁別の獲得に与える抗コリン薬の効果
関西心理学会第109回大会, 1997 - ラットの時間弁別行動に与える抗コリン薬の効果（2）
日本動物心理学会第56回大会, 1996 - PI手続きによるラットの時間弁別行動に与える海馬采-脳弓損傷の効果
日本心理学会第60回大会, 1996, Poster presentation - ラットの時間弁別行動に与える抗コリン薬の効果
日本動物心理学会第55回大会, 1995, Poster presentation - アメフラシの感作とネズミの逃避学習におけるC/EBPとc-fos遺伝子発現
日本分子生物学会第18回大会, 1995, Poster presentation - Morris型水迷路におけるラットの空間学習行動の発達
日本動物心理学会第54回大会, 1994
Research Projects
- 時間の長さの記憶形成を支える神経基盤の解明
畑 敏道
日本学術振興会, 科学研究費助成事業, 2022/04 -2025/03, 基盤研究(C), 同志社大学 - Psychological approach to improving the effectiveness of Earthquake Early Warnings
Nakayachi Kazuya
This research project investigated why protective actions were not taken by individuals despite receiving Earthquake Early Warnings (EEWs), and explored ways to promote protective actions. Residents were surveyed, and results confirmed that mobile phones were the primary devices through which EEWs were received. The results also revealed that residents viewed their phone screens immediately after receiving the EEWs, hindering their ability to take protective actions instantly. We examined the effects of a drill based on conditional discrimination learning. The results of subsequent experiments did not support our hypothesis that trained participants would pay attention to the correct subject in a shorter reaction time during certain situations compared to untrained individuals., Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2020/07 -2022/03, Grant-in-Aid for Challenging Research (Exploratory), Doshisha University - Development of rat behavior model of free-rider avoidance
Hata Toshimichi
In the present study, two rats were placed in a single box, and experiments were conducted under multiple conditions in which not only Rat A but also the other Rat B was fed or not fed depending on the lever pressing response of Rat (A). We found that the number of lever presses by Rat A differed depending on whether the other rat was fed or not, specific to the situation in which the Rat A did not obtain food. These findings indicate that animals' responses differed depending on the number of reinforcers obtained by the other individual, suggesting that rats may respond differently to an unfair reward distribution than to a fair one., Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2019/04 -2022/03, Grant-in-Aid for Scientific Research (C), Doshisha University - 成果を横取りする他者に対する利益分配忌避のラット行動モデルの確立
萌芽研究, 2017 -2019, Competitive research funding - ラットの時間弁別行動を担う神経基盤の多面的解析
若手研究（Ｂ）, 2011 -2014, Competitive research funding - Total research to prevent falling away from therapeutic program for obesity by psychological techniques
SATO Suguru; AOYAMA Kenjiro; HATA Toshimichi
In this study, it is hypothesized that the negative emotion would disturb the controlling of eating behavior. This procedure reduced the amount of snack intake after the lunch. The first study was done by Aoyam. In the experiment, participants were asked to input the contents of their lunch into their cell phones to facilitate their memory about the lunch. The second study was done by Hata. Using rats, it was examined the effect of the restriction of high-fat food and the enhancement of the sympathetic adrenal medullary(SAM) axis on the choice of high-fat food. It was shown that the choice of high-fat food increased following enhancement of the SAM axis irrespective of the experience of food restriction. The third study was done by Sato. It was reported that negative emotion disturbed the controlling of body weight reducing., Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2009 -2011, Grant-in-Aid for Challenging Exploratory Research, Doshisha University - Neuroscientific studies on the effect of moxibustion on chronic diseases
USUDA Nobuteru; SUGIYAMA Satoshi; NAGATSU Toshiharu; MURAKAMI Kazuo; NAKAI Sachiko; WATARI Nakazou; NAGATSU Ikuko; NAKAHARA Daiichirou; HIGUCHI Susumu; TAKAHASHI Hisahide; HATA Toshimichi; HAYASHI Takashi; FUKASAWA Motoaki; ATSUZAWA Kimie; MATSUZAWA Ayami; YAMAZAKI Masao; NAGAOKA Toshiharu; OKAWARA Takeshi; SETOU Mitsutoshi; OOSUKA Kouzi; KANEKO Rina
Subjective evidence of the brain reactions for moxibustion was attempted. Moxibustion treatment was done on rats, and measurements of brain functions based on neurotransmitter secretion by microdialysis; electrophysiological changes including EEG ; and gene expression analyses by DNA microarray, were performed. As all the reaction measured was very weak, high S/N ratio was required. Dopamine secretion, elevated gene expression, the elevation of body temperature, changes of hippocampal θwave in EEG, were shown in the experiments. As these are considered to affect brain functions including emotion, memory, etc, moxibustion may have possible curative effects on chronic diseases., Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2008 -2010, Grant-in-Aid for Scientific Research (B), Fujita Health University - 報酬に基づく学習に関与する脳内メカニズムの解明
若手研究（Ｂ）, 2007 -2008, Competitive research funding - Effects of maternal stress on brain and emotional/motivational functions in adolescence
NAKAHARA Daiichiro; ISHIDA Yasushi; HATA Toshimichi
Maternal stress during pregnancy may have an adverse effect on brain and behavioral development of the affected offspring. We examined; (1) if maternal stress influences cytogenesis in adolescent brain; (2) how maternal stress alters corticosterone secretion; (3) whether maternal stress affects the ability of acute and chronic cocaine administration to potentiate and depress the rewarding effects of electrical stimulation of the medial forebrain bundle (MFB) using intracranial self-stimulation (ICSS); (4) how maternal stress changes the extinction of the MFB stimulation response. Male offspring of female rats that were prenatally stressed or unstressed was used in the present experiment. Prenatal stress treatment was performed daily from gestational days 13 to 19. The dams were put into a Bolman cage and exposed to bright light for 45 min three times a day. The results showed the following: (1) maternal stress induced a decrease in newborn cells of several brain regions related to emotional/motivational functions; (2) maternal stress caused a prolonged post-stress corticosterone secretion in offspring following restraint stress; (3) maternal stress affected neither the potentiating effects of the rewarding impact of the MFB stimulation induced acutely by exposure to cocaine, nor its depressant effects during the withdrawal periods in repeated drug exposures; (4) maternal stress augmented responding during extinction of ICSS with cocaine treatment in offspring. The findings indicate that maternal stress may reduce cytogenesis and negative-feedback of the hypothalamic-pituitary-adrenal axis, whereas increase resistance to extinction of responding for a reward under cocaine loading in offspring., Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2005 -2007, Grant-in-Aid for Scientific Research (B), Hamamatsu University School of Medicine - 脳内報酬系に関する生理心理学的研究
科学研究費補助金, 2007, Competitive research funding - 情報処理モデルからみたラットの時間弁別行動と脳機能系の解明
特別研究員奨励費, 1998 -1999, Competitive research funding - 動物の時間弁別行動に関する生理心理学的研究
科学研究費補助金, 1994, Competitive research funding - 蔗糖、トリプトファン投与の際のラットの記憶改善の研究
NPO法人「食と健康プロジェクト」, 各種団体からの研究助成, Competitive research funding